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African-Caribbean ethnicity key risk factor for sight-threatening diabetic eye disease
People of African-Caribbean ethnicity with Type 2 diabetes are a third more likely to develop a condition called sight-threatening diabetic retinopathy (STDR) than other ethnic groups, according to researchers from King’s College London. The study, published in the journal Diabetes...Take part in the 'Whole Eye OCT Experience' at 100% Optical 2024
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Predicting outcomes in repair of canalicular lacerations
This is a retrospective study looking at results of primary canalicular repairs in a tertiary eye centre. Thirty-nine patients were included in the study. The cause of injury was blunt trauma in 51.2%, road traffic accident (RTA) in 30.7%, animal...
The inflammatory side-effect of Brimonidine
Brimonidine is a well established selective alpha-2 adreno-receptor agonist, used to lower intraocular pressure. This case series reports on 19 eyes affected by brimonidine induced uveitis. Mean age of the patients was 74 years and mean duration of brimonidine use...
AlloDerm for correction of lower lid retraction
This is a retrospective review of 95 eyes of 54 patients undergoing orbital decompression for Graves’ orbitopathy. All patients had a swinging eyelid approach across the whole of the lower lid. Thirty-six eyes also had insertion of a 0.3mm thick...
IAC vs. IVC chemotherapy for RB
This a single centre retrospective review of consecutive patients between 1997 and 2014, of all sporadic unilateral retinoblastoma (RB) group D cases, treated with combined intravenous chemotherapy (IVC) and focal treatments (1997- 2008), or intra-arterial chemotherapy (IAC) treatment (2008 to...
A phase 3 randomised trial of nicotinamide for skin cancer chemoprevention
To B3, or not to B3? That was the question asked in this controlled trial in which the authors were able to show that oral nicotinamide (vitamin B3) is able to reduce further skin cancer development in high risk patients....
Ocular Trauma Scores in paediatric open globe injuries
This is a retrospective case series of 71 open globe injuries in children of less than 18 years of age, with a minimum follow-up period of one year, between 1 September 1992 to 31 July 2011, from the Eye Department...
Comparison of bleb grading and IOPs
The purpose of this study was to compare a novel anterior segment optical coherence tomography (AS-OCT) bleb grading system with a clinical bleb grading system (Moorfields) and both with intraocular pressure (IOP) levels following trabeculectomy surgery. The authors developed a...
OCTA and pigment epithelium detachments
Yannuzzi et al. report on their study aiming to evaluate the ability of optical coherence tomography angiography (OCTA) to differentiate vascularised from nonvascularised pigment epithelium detachments (PEDs) using conventional imaging techniques, including fundus fluorescein angiography (FFA) and indocyanine green (ICG),...
Injection of methotrexate into silicone oil-filled eyes for grade C PVR
Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...
