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The Duke Elder Exam of Ophthalmology: A Comprehensive Guide for Success
The Duke Elder Exam is an annual competitive national undergraduate exam organised by the Royal College of Ophthalmologists. This two-hour exam consists of 90 multiple-choice questions (MCQs) and examines clinical ophthalmology, ocular physiology, anatomy, pathology, genetics and socio-economic medicine related...
Topography-guided photorefractive keratectomy in the treatment of corneal scarring
This study reports the outcome of topography-guided photorefractive keratectomy (TG-PRK) in the treatment of patients with corneal scarring. A retrospective case series including six eyes of six patients with corneal scarring and irregular astigmatism who underwent topography guided PRK. The...
Predicting outcomes in repair of canalicular lacerations
This is a retrospective study looking at results of primary canalicular repairs in a tertiary eye centre. Thirty-nine patients were included in the study. The cause of injury was blunt trauma in 51.2%, road traffic accident (RTA) in 30.7%, animal...
The inflammatory side-effect of Brimonidine
Brimonidine is a well established selective alpha-2 adreno-receptor agonist, used to lower intraocular pressure. This case series reports on 19 eyes affected by brimonidine induced uveitis. Mean age of the patients was 74 years and mean duration of brimonidine use...
IAC vs. IVC chemotherapy for RB
This a single centre retrospective review of consecutive patients between 1997 and 2014, of all sporadic unilateral retinoblastoma (RB) group D cases, treated with combined intravenous chemotherapy (IVC) and focal treatments (1997- 2008), or intra-arterial chemotherapy (IAC) treatment (2008 to...
A phase 3 randomised trial of nicotinamide for skin cancer chemoprevention
To B3, or not to B3? That was the question asked in this controlled trial in which the authors were able to show that oral nicotinamide (vitamin B3) is able to reduce further skin cancer development in high risk patients....
Three years of experience with quantiferon-TB Gold Testing in patients with uveitis
Quantiferon-TB Gold is a new alternative to the tuberculin skin test that utilises synthetic peptides representing M. tuberculosis antigens ESAT-6, CFP-10, TB7.7 and upon incubation with whole blood IFN-γ is released from pre-sensitised T cells and can be measured by...
Ocular Trauma Scores in paediatric open globe injuries
This is a retrospective case series of 71 open globe injuries in children of less than 18 years of age, with a minimum follow-up period of one year, between 1 September 1992 to 31 July 2011, from the Eye Department...
OCTA and pigment epithelium detachments
Yannuzzi et al. report on their study aiming to evaluate the ability of optical coherence tomography angiography (OCTA) to differentiate vascularised from nonvascularised pigment epithelium detachments (PEDs) using conventional imaging techniques, including fundus fluorescein angiography (FFA) and indocyanine green (ICG),...
Injection of methotrexate into silicone oil-filled eyes for grade C PVR
Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...
Sutureless, scleral fixated-IOLs
This was a retrospective cohort study of 112 sutureless, scleral-fixated posterior chamber intraocular lens implantations (SSFCIOL) over a four-year time period. Mean follow-up duration was 13.0 ±10.4 months. The primary indication for SSFCIOL was dislocation of IOL due to zonular...
