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Experiences of patients and their families and the impact of Leber hereditary optic neuropathy

The authors present a qualitative study which aimed to explore the impact of Leber hereditary optic neuropathy (LHON) from diagnosis to present day on both patients and their families. Individuals with LHON and their families were purposively sampled from four...

Did the COVID-19 pandemic affect quality of life of patients newly diagnosed with intra-cranial hypertension?

Coronavirus disease 2019 (COVID-19) was identified as a global pandemic by the World Health Organization in March 2020. This article aimed to explore how the care of patients with idiopathic intra-cranial hypertension (IIH) was affected during the COVID-19 lockdown. The...

Bleomycin for conjunctival lymphangioma

This is a retrospective review of 16 eyes which underwent intralesional / sub-conjunctival injections of bleomycin sclerotherapy for conjunctival lymphatic malformations (lymphangiomas). The mean age was 18 (range three to 59 years). Four of the lesions were microcystic and 12...

Incomplete teprotumumab treatment for thyroid eye disease

This is a multi-centre retrospective analysis of clinical outcomes in patients who were on teprotumumab for thyroid eye disease but had the usual regime of eight infusions, three weeks apart, interrupted due to COVID-19. Manufacturing was suspended between Dec 2020...

Pilot trial of Fluoxetine for post-stroke homonymous hemianopia

The authors present a pilot randomised placebo controlled double blind trial assessing 20mg fluoxetine once daily for 90 days versus placebo in stroke survivors with isolated homonymous hemianopia. Exclusion criteria were extensive in terms of pre-existing ophthalmic or neurologic disease,...

Cost-effectiveness framework discussion for vision screening

The authors present a discussion paper on hypothetical, but representative, examples of post-referral costs that may result from different screening options up to the point of discharge from specific services. Data was taken from a recent (2019) systematic review (with...

Treatment of progressive keratoconus

This study aimed to analyse the clinical results of accelerated iontophoresis-assisted epithelium corneal cross-linking (i-ON CXL) to evaluate the risk factors for keratoconus progression after treatment, and the safety and efficacy of re-treatment using epithelium-off CXL protocol in paediatric patients....

Impact of initial management on relapse in Vogt–Koyanagi–Harada syndrome

In this retrospective, multi-centre, observational study, the impact of the initial management of Vogt-Koyanagi-Harada syndrome (VKHS) was assessed by reviewing the records of all patients diagnosed with VKHS between January 2001 and December 2020 in two French tertiary centres, with...

Clinical and anatomical differences for heavy eye syndrome, highly myopic sagging eye syndrome, and sagging eye syndrome

The authors explored the mechanisms underlying the development of heavy eye syndrome (HES), highly myopic sagging eye syndrome (SES)-like, and SES with the aim to differentiate the three conditions clinically and anatomically to aid treatment decision-making. This was a retrospective...

Horizontal recti injection of botulinum toxin for treatment of infantile nystagmus

In this study the authors aimed to demonstrate the effect of botulinum toxin (BT) on the frequency of ocular oscillation in children with infantile nystagmus syndrome (INS). Botulinum toxin was administered with direct injection into the horizontal recti muscles using...

Profile of presentation, follow-up and management of orbital myositis

This retrospective study reviewed the demographic characteristics of patients with orbital myositis, their clinical profile, management options, outcomes and predictive factors for recurrence. The study included 52 patients (55 eyes; 3% bilateral involvement), 36 females, with mean age at presentation...

Feb/Mar 2015 Quiz 1

A 79-year-old male presented to the ophthalmic emergency department with a three week history of left eye pain. He also reported visual deterioration in the left eye over the same period. He suffered from degenerative myopia, with his spectacle prescription...