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Orbital cellulitis - an overview of the diagnosis and management

1 February 2022 | | EYE - Orbit, EYE - Neuro-ophthalmology, EYE - Imaging, EYE - General
Periorbital (preseptal) and orbital cellulitis are infections of the subcutaneous tissues of the eye. They are differentiated by the location of the infection. Periorbital cellulitis refers to infection of the eyelid and subcutaneous tissues anterior to the orbital septum, whereas...

Time is vision in central retinal artery occlusion

4 August 2021 | | EYE - Vitreo-Retinal, EYE - General
Central retinal artery occlusion (CRAO) is a rare but devastating vascular episode that can have severe impact on vision. Treatment is very time-limited and needs to be initiated very quickly to salvage any vision. The majority of patients present to...

Poppers retinopathy: What is it and how do we treat it?

2 June 2025 | | EYE - Vitreo-Retinal
Poppers retinopathy is a relatively unknown phenomenon which afflicts users of poppers but should be considered as a differential in sudden-onset or sub-acute visual acuity loss – particularly in patients with a history of recreational drug use. Raising awareness of...

Progressive myelination of the retinal nerve fibre layer: Acquired or incidental?

4 August 2025 | | EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Paediatrics
*Co-first authors.Myelinated retinal nerve fibres are retinal nerve fibres encased by a myelin sheath, located anterior to the lamina cribrosa [1]. First described by Virchow in 1856, a myelinated retinal nerve fibre layer (RNFL) appears as a whitish, feathery patch...

Understanding spaceflight-associated neuro-ocular syndrome (SANS): what do we know?

2 August 2022 | | EYE - Oculoplastic, EYE - General
Introduction Formerly known as visual impairment and intracranial pressure syndrome (VIIP), space-related neuro-ocular syndrome (SANS) is defined by a collection of ophthalmic and neurological findings in astronauts after long-term spaceflight [1]. Changes in the eyeball, such as hyperopic shift, during...

Breakthroughs in the genetics of angle-closure glaucoma

1 April 2017 | | EYE - Glaucoma
Angle closure glaucoma (ACG) is not widely known to be a familial condition, yet the recent explosion of genetic data and large scale genome wide investigations have confirmed at least 13 genetic loci associated with ACG [1], and provided some...

‘Phaco-plus’ procedures at forefront of modern glaucoma management

3 June 2026 | | EYE - Cornea, EYE - Cataract
Glaucoma and cataract increasingly present as a ‘two-in-one’ surgical opportunity. In the UK, new modelling suggests ~1 million adults aged ≥40 may currently have glaucoma, with a projected rise to ~1.6 million by 2060 as the population ages and demographics...

Pigmented paravenous retinochoroidal atrophy

4 December 2024 | | EYE - Imaging, EYE - Vitreo-Retinal
Presentation A 46-year-old Caucasian female was referred to the eye clinic by her local optician following a routine sight test. She was noted to have pigmentary retinal changes in both eyes but was asymptomatic with no visual complaints. At presentation...

Ocular manifestations of multiple sclerosis: an overview

1 December 2022 | | EYE - Neuro-ophthalmology, EYE - Pathology
Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS), in which there is dissemination of lesions in time (two or more clinical events) and space (multiple lesions seen on brain and spinal imaging). The pathophysiology...

The eye as a window to the brain: Non-invasive neuromonitoring

3 June 2026 | | EYE - Imaging, EYE - Neuro-ophthalmology
This article has been verified for CPD. Click the button below to answer a few short questions and download a form to be included in your CPD folder. Neuromonitoring, for example in conditions causing raised intracranial pressure (ICP) such as...

What's trending Apr/May 2025

2 April 2025 | | EYE - Cornea, EYE - Oculoplastic, EYE - Imaging, EYE - Vitreo-Retinal, EYE - Oncology
A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #ContactLens #Trapped I started wearing contact lenses in my teenage years and was always worried about them slipping behind my eyes....

Behind the eyes: Unravelling the mystery of a painless progressive proptosis

4 February 2025 | | EYE - Oculoplastic, EYE - Orbit, EYE - Pathology
Orbital fungal infections have the potential to give rise to serious complications. While these infections typically originate in the sinuses, patients may initially exhibit ocular symptoms. As a result of the diverse and often vague clinical manifestations (especially during the...