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Risk of CNV related to angioid streaks in PXE

7 April 2021 | | EYE - Vitreo-Retinal
This retrospective cross-sectional study investigated 301 patients with pseudoxanthoma elasticum (PXE) for prevalence of choroidal neovascularisation (CNV) and macular atrophy. Some patients were excluded due to missing or poor-quality imaging or the fact that they didn’t have angioid streaks, leaving...
Ophthalmic Research journal cover image

Changes in drusen and retinal layer volumes prior to CNV development

7 April 2021 | | EYE - Vitreo-Retinal | Age-related macular degeneration, Choroidal neovascularisation type, Drusen load, Imaging biomarkers, Retinal layer volumes
This retrospective longitudinal study looked at patients with wet age-related macular degeneration (AMD) in one eye who subsequently developed wet AMD in the fellow eye. The aim was to discover whether drusen characteristics or volumes of retinal layers correlate with...
British Journal of Ophthalmology cover image.

Aflibercept (AF) for age-related macular degeneration (ARMD): four-year outcomes of a ‘’treat-and-extend’ (T&E) regimen with exit-strategy

3 October 2022 | | EYE - Vitreo-Retinal | Neovascularisation, Retina, Vitreous
This is a retrospective observational study of 82 patients, between 2014 to 2016 from Switzerland of treatment-naive patients with nARMD, treated with AF, with specific T&E protocol without a loading phase and predefined exit criteria and patients were observed three...

The use of virtual reality in paediatric ophthalmology

4 August 2025 | | EYE - Paediatrics
The purpose of this study was to investigate the utility of virtual reality (VR) in the broader field of paediatric ophthalmology with review of examination, screening, diagnosis, prevention and treatment. This review also explores the potential of eye tracking used...

The implementation of postoperative day 1 vitrectomy telephone follow-up consultations

6 April 2021 | | EYE - Vitreo-Retinal, EYE - Glaucoma, EYE - General
In this pre-COVID-19 study, the authors argue that some follow-up consultations can be done by telephone without compromising patient safety. Thirty years ago, a study by Isernhagen et al. [1] found that 52% of patients required some form of unexpected...

Irido-corneal endothelial syndrome: an overview

24 January 2022 | | EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - General
Irido-corneal endothelial (ICE) syndrome is a rare group of eye related disorders that constitute three different clinical entities: Chandler syndrome (CS), essential / progressive iris atrophy and iris naevus / Cogan-Reese syndrome. ICE syndrome is sporadic in its presentation as...

What's trending Dec/Jan 2023

1 December 2022 | | EYE - General
A round-up of the eye related hot topics that have been trending on social media over the last few weeks. #frightnight #halloween #protectyoureyes The Royal College of Optometrists advised the public against wearing novelty contact lenses this Halloween. In a...

Cavernous sinus syndrome

4 February 2021 | | EYE - Neuro-ophthalmology, EYE - General
Anatomically the cavernous sinus is a plexus of multiple veins that are connected and within this plexus there are several important vascular and neurological structures. These include cranial nerves III, IV, V1 (and sometimes V2), VI as well as the...

Ophthalmic viscoelastic devices: Useful insights for a novice cataract surgeon

4 February 2025 | | EYE - Cataract
Ophthalmic viscoelastic devices (OVDs) are essential in many different stages of cataract surgery. This article discusses the categories of OVDs and their respective properties, and highlights their uses in different scenarios faced in cataract surgery. Ophthalmic viscoelastic devices are gel-like...

How to examine the visual system Part 2: Accommodation, pupils, fundoscopy and additional tests

1 August 2014 | | EYE - Vitreo-Retinal
Examining the visual system can be a tricky skill for medical students to master, yet it is a task that is frequently tested in examinations. This is the second of a two-part series of articles, which together aim to improve...

Can e-learning help bridge the ophthalmology teaching gap?

1 February 2022 | | EYE - General
The authors ask whether e-learning can help to address the current lack of ophthalmology teaching in the undergraduate curriculum. Studies among the United Kingdom, Australasian, Canadian and Asian medical schools have found that students on average spent just over a...

Effect of minor trauma in eyes with previously undiagnosed angioid streaks

1 April 2014 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Angioid streaks (AS) may be associated with pseudoxanthoma elasticum (PXE), Paget’s disease, haemoglobulinopathies, Ehlers-Danlos Syndrome or abetalipoproteinaemia. Histopathology showed retinal pigment epithelium (RPE) and choriocapillaris loss, elastic fibre degeneration, calcium deposition, active choroidal neovascular membrane (CNVM) and vascular endothelial growth...