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2904 results found

The effect of everolimus on retinal pigment epithelium and proliferative vitreo-retinopathy

The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...

Pterygium ocular surface temperature

This prospective study investigated the ocular surface temperature in patients with pterygia compared to those with dry and healthy eyes respectively. Previous studies have shown that patients with dry eyes show a significant decrease in ocular surface temperature on sustained...

Vision measurements vs. self-rating

The aim of this study was to evaluate the association between self-rated vision status and tests of visual acuity, contrast sensitivity, stereoacuity, bilateral visual field and self-reported visual function in specific domains of near and far vision. The goal was...

Intermittent exotropia

Four cases of intermittent exotropia are discussed. Case 1 was a nine-month-old with cycloplegic refraction of +1.0DS and a 30PD intermittent exotropia at near and distance. Discussions considered observation, part-time occlusion, refractive correction and later possibility of surgery. Case 2...

Video game play as amblyopia treatment adjunct

The aim of this study was to evaluate the role of monocular video game play as a supplement to occlusion therapy in the treatment of anisometropic amblyopia (AA). This was a prospective study of 68 patients aged six to 14...

Nanoparticle administration of latanoprost

Glaucoma is a progressive optic neuropathy characterised by increased ocular pressure and loss of retinal ganglion cells. Conventional drug therapy with eye drops to reduce intraocular pressure (IOP) has variable bioavailability and can lead to ocular surface disease. In this...

The decline in attentional visual fields in the Salisbury Eye Evaluation Driving Study

The purpose was to document changes in attentional visual field (AVF) over time and analyse the possible baseline characteristics predicting a decline in AVF size over time. Data was taken from a sample of 968 individuals. The authors found a...

Reliability of Fluorescein Dye Disappearance Test (FDDT)

The authors look at the role of the FDDT in the evaluation of adults with primary acquired nasolacrimal duct obstruction (PANDO) and its correlation with the age and severity of epiphora. They report the results of a prospective cross-sectional comparative...

Hormonal contraceptives and IIH

This multicentre retrospective population based case control study investigated whether there was a higher incidence of idiopathic intracranial hypertension (IIH) in those patients taking oral contraceptive pills (OCP) and other hormonal contraceptives. Fifty-three women were diagnosed with IIH between Jan...

Effects of idiopathic intracranial hypertension on the optic nerves

The authors review the latest evidence regarding how the optic nerves are affected by idiopathic intracranial hypertension (IIH), possible pathophysiology and methods of assessment. IIH is described as a clinical syndrome of raised intracranial pressure of unknown aetiology. A systematic...

Correlation of parent observations vs. clinical measures of exotropia

The purpose of this study was to compare the parental observations with the clinical evaluation findings in paediatric patients with intermittent exotropia and to determine the clinical factors associated with the parental observations. The study included 100 parents of 95...

Vitreoretinal lymphoma: The importance of cerebral spinal fluid evaluation at initial diagnosis

This is a retrospective single centre case observational study between 2006 and 2024 at Memorial Sloan Kettering Cancer Center, to review patients with biopsy-proven central nervous system lymphoma and MRI brain evaluation. Sixth-five patients were included in this study, 11...