The relationship between refractive outcomes and biometric parameters were evaluated following intravitreal Bevacizumab (IVB) monotherapy. Sixty-three infants were grouped into 1) infants treated with VB monotherapy for ROP (six with zone 1 and eight with posterior zone II retinopathy of prematurity (ROP)); 2) infants treated with laser photocoagulation for ROP (three with zone 1 and 25 with zone 2); and 3) infants with spontaneous regressed ROP without any anatomical sequelae (n=21). Incidence of myopia was significantly lower in group 3 (11.8%) than groups 1 (40.7%) and 2 (32.7%). Group 2 had significantly thicker lenses than groups 1 and 3. Group 1 had significant association between spherical equivalent and axial length; reducing spherical equivalent with increasing axial length. Group 2 had significant association between spherical equivalent and anterior chamber depth; both positively correlated.
ROP ocular outcomes after Bevacizumab treatment
Reviewed by Fiona Rowe
Evaluation of refractive errors and ocular biometric outcomes after intravitreal Bevacizumab for retinopathy of prematurity.
CONTRIBUTOR
Fiona Rowe (Prof)
Institute of Population Health, University of Liverpool, UK.
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