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Cavernous sinus thrombosis and orbital cellulitis

This is a report of six cases of combined orbital cellulitis and infective cavernous sinus thrombosis, with a literature review. The average age was 39 years, four were male and two were intravenous drug users. All had sinusitis, usually involving...

Corneal crosslinking in pellucid marginal degeneration

Fourteen studies were included in this first review examining the use of corneal-crosslinking (CXL) to treat pellucid marginal degeneration (PMD). PMD is a bilateral, non-inflammatory corneal thinning disorder characterised by inferior peripheral corneal thinning 1-3mm from the limbus in the...

Globe subluxation subsequent to long-term steroids

Globe subluxation, when the globe equator projects anterior to the orbital rim, is a serious orbital condition commonly associated with thyroid eye disease, floppy eye syndrome or a shallow orbit. The authors present a first case of a spontaneous globe...

Aspirin and upper lid surgery

This is a double-blind randomised controlled trial of preoperative aspirin versus placebo in patients undergoing upper lid blepharoplasty or ptosis surgery. All enrolled patients were already taking aspirin and no other anti-platelet or anticoagulant drugs. All patients either had no...

The use of adalimumab for relapse in patients with Vogt-Koyanagi-Harada disease

In this retrospective, multi-centre, cohort study, the efficacy and safety of Adalimumab (ADA) treatment for the exacerbation or recurrence of Vogt-Koyanagi-Harada (VKH) patients was assessed by investigating the medical records of patients who had received ADA treatment for more than...

Low-dose bimatoprost/timolol gel: a new fixed-combination option

This phase III international randomised trial evaluated the efficacy and safety of a new low concentration bimatoprost/timolol eye gel (bimatoprost 0.01%/timolol 0.1%). It was compared with the conventional higher-strength fixed combination eye drops (bimatoprost 0.03%/timolol 0.5%) in patients with open-angle...

Thermal injury and false eyelashes

The authors provide a case of cyanoacrylate glue causing a thermal burn on the eyelid and explain how this type of burn should be managed. The use of false lashes as well as the techniques used to apply them come...

Simulated ocular surgery

See also Simulated ocular surgery - strabismus surgery and Simulated ocular surgery: pars plana vitrectomy and scleral buckling surgery This is the first of a series of articles that will have three aims. Firstly, to demonstrate why simulated ocular surgery...

Stem cell transplantation and pterygium surgery

Pterygium is a benign, fibrovascular overgrowth of bulbar conjunctiva extending onto the cornea and has been associated with ultraviolet (UV) light exposure. The prevalence of pterygium worldwide varies between geographical zones but has been reported to range between three and...

The Story of Looking: Mark Cousins

Lake, Sweden, as featured in The Story Of Looking. In an interview with Director Mark Cousins about his relationship with sight and storytelling, Peter Cackett discusses Cousins’ recent film, The Story of Looking, and how its production informed, and was...

My Top Five: Promising gene therapies for ocular conditions

Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

My Top Five: Promising gene therapies for ocular conditions

Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...