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RTP801 as a neuroprotective and axon regenerative treatment

This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...

Ocular Dirofilariasis: a diagnosis on the rise?

Dirofilaria repens is one of 40 species of Dirofilaria. It is a zoonotic filarial nematode that commonly impacts dogs, however, human infection can occur through affected organs like skin, lung and eyes [1]. Although, there have been case reports of...

A missed opportunity

Back in 2000 Sir Liam Donaldson wrote a piece of work commissioned by the then Secretary of State for Health entitled “An Organisation with a Memory”. We are now 18 years on and still some of the recommendations from them...

Foundation Post in Ophthalmology

If you are in your final year of medicine at university, firstly congratulations on making it so far and secondly, you may be wondering how and which jobs to rank highly. If you have found yourself reading this article, then...

From paper to digital: Real lessons for a sustainable NHS digital future

Portsmouth's OpenEyes implementation reveals why healthcare digital transformation needs honest evaluation, proper clinical leadership resourcing and realistic expectations about technology efficiency promises. Like many eye departments across the NHS, we at Portsmouth were drowning in paper. Notes went missing, handwriting...

Isolated trochlear (fourth cranial) nerve palsy in an Asian population

The authors report on 35 consecutive new cases of isolated fourth cranial nerve palsy seen over a period of six months in one neuro-ophthalmology clinic in Southeast Asia, with emphasis on their aetiology and management. We report on 35 patients...

SightCare wins Service Excellence Award at INSPIRE Business Awards 2024

We are thrilled to announce that SightCare has won the Service Excellence Award at the Inspire Awards 2024! SightCare was selected by the judges because it was felt that “they were pushing the boundaries and trying to move the business...

Changes in the prevalence of myopia in middle-aged caucasian Australians compared to UK biobank

This article compares rates of myopia and high myopia in large cohorts of caucasian Australians from the Busselton Healthy Ageing Study, the urban Gen1 of the Raine Study, the Blue Mountains Eye study and Melbourne Visual Impairment Project. The former...

African-Caribbean ethnicity key risk factor for sight-threatening diabetic eye disease

People of African-Caribbean ethnicity with Type 2 diabetes are a third more likely to develop a condition called sight-threatening diabetic retinopathy (STDR) than other ethnic groups, according to researchers from King’s College London. The study, published in the journal Diabetes...

Ophthalmology research: lessons from the Academic Foundation Programme

The author discusses practical lessons learned during eight months of ophthalmology research as a guide for candidates considering a research themed AFP post, with general tips for anyone undertaking research whilst balancing clinical duties. Ophthalmology is already one of the...

Don’t miss Optometry Tomorrow 2024

There is still time to register for the College of Optometrists’ flagship event, Optometry Tomorrow.

Celebrating the winners of the ANTS 2026 Imaging Competition

Sponsored by The ANTerior Segment 2026 Imaging Competition from Eye News and Keeler celebrates its third year of outstanding work by ophthalmic imagers and is proud to present to you its three winners and honorary mentions. Your judges – Nicola...