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MicroRNA inhibits corneal neovascularisation
MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...
A case report of cavernous sinus syndrome following dental procedure
This case report describes a patient presenting with painful diplopia as a consequence of root canal dental treatment. Following root canal treatment a non-resolving tooth pain led to a decision to extract the tooth, leading to onset of severe periorbital...
Enzymatic clearance of anterior chamber infiltrate in uveitis
Aqueous humour (AH) which fills the anterior chamber (AC) of the eye provides nutrients to the cornea and the lens. Clearance of cellular and particular matter from AH is necessary for good visual acuity. In part this is achieved by...
Efficacy of browpexy with blepharoplasty
This is a retrospective case series evaluating the efficacy of and comparing the surgical results between internal (IB) and external browpexy (EB) surgery in lifting central and lateral brow. Patients who underwent blepharoplasty without brow lift were used as a...
Long-term results of cross-linking treatment for keratoconus
The authors report on the long-term outcomes in a prospective case series of patients with keratoconus undergoing corneal collagen cross-linking (CXL) treatment. Thirty-two patients (40 eyes; mean age 22.5+/-5.5 years) with Grade I, II and III progressive keratoconus were recruited...
The effects of ab-interno XEN gel implantation on postural IOP elevations
The study involved 18 patients with XEN gel implants, 30 patients who had trabeculectomy, and 30 medically managed glaucoma patients. All patients in XEN gel implant and trabeculectomy groups had at least 11 months of follow-up following successful surgery resulting...How to be a better optometrist – a personal view
Our optometry editor shares her personal observations of what makes the best optometrist. Some years ago in Glasgow, I gave a presentation with this same title, ‘How to be a better optometrist’. I was the optometry programme director for NHS...The management of chronic uveitis
A 40-year-old company executive is referred from another unit with recurrent anterior and posterior uveitis for 12 months and the inflammatory markers are raised. Review of systems This is a case of chronic uveitis which needs a thorough workup and...Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants
“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...Acute management of retrobulbar haemorrhage
The authors discuss the importance of rapid diagnosis and correct management of acute RBH presentation to avoid the risk of permanent blindness. Retrobulbar haemorrhage (RBH) is an ocular emergency that occurs due to arterial bleeding in the orbital cavity behind...
