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A personal reflection: working at the International Centre for Eye Health from 2006–2024
I feel incredibly fortunate to have been working part-time at the International Centre for Eye Health (ICEH) [1] since 2006. Earlier in my career, the responsibilities of work and a growing family made this merely an aspiration, and apart from...Investigating the link between corneal clarity and statin use
Transparency is a vital attribute of the cornea, necessary in preserving healthy vision. Maintaining this requires the collective input of the various layers of the cornea. Mostly, the layers implicated in this are the corneal stroma and endothelium [1]. Our...Strengthening the signal: Advancing oculomics research for systemic health insights
Oculomics, the study of how ocular structure reflects systemic health, is poised to become an integral tool for predicting, triaging, and diagnosing a wide range of diseases. By analysing data from the eye, particularly the retina, healthcare providers can gain...
Pseudophakic Monovision: A Clinical Guide
The contents of this small volume should provide useful tips for all ophthalmic practitioners involved with managing patients undergoing cataract surgery. For those ophthalmic clinicians and supporting staff not familiar with the potential options for achieving a spectacle independent refractive...Quality matters in the management of serious eye disorders
The author discusses the first quality standard for serious eye disorders from NICE and takes a look at new care models for enhanced service delivery. Patient backlogs pose risks to patient safety, with research showing that people are losing sight...Acute uveitis from late migration of soft lens matter 10 years post cataract surgery
A 58-year-old Caucasian male presented to the emergency eye clinic with a two-day history of a painful, red left eye and blurred vision. His past ocular history included uncomplicated left phacoemulsification cataract surgery in 2010 and left retinal detachment repair...
Topical insulin for neurotrophic ulcers
This retrospective case series described the use of topical insulin drops as an aid in treatment of refractory neurotrophic corneal ulceration in six patients. Insulin drops were prepared under sterile conditions from standard insulin preparations mixed with artificial tears containing...
Treatment of Sjogren’s Syndrome dry eye in mouse model
Sjogren’s syndrome (SS) is a chronic autoimmune disease characterised by inflammation of the exocrine glands, specifically the salivary and lacrimal glands that produce saliva and tears, respectively. The immune-mediated attack on the salivary and lacrimal glands leads to the development...
Placement of an eyelid weight as an upper lid spacer for lagophthalmos
Upper lid loading with a weight is a well described procedure for the treatment of lagophthalmos and exposure keratopathy. The authors describe a modification of this procedure whereby the levator aponeurosis is recessed in combination with supratarsal weight implantation. The...
MicroRNA mediate retinoblastoma signal transduction
MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...
MicroRNA inhibits corneal neovascularisation
MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...
