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My Top Five: Promising gene therapies for ocular conditions
Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...Leveraging networks and collaboration: The Calabar Diabetic Retinopathy Service, from inception to a state-wide service, research and training hub
Diabetic retinopathy (DR), a microvascular complication of diabetes mellitus (DM), is a leading cause of preventable vision loss and blindness in people of working age globally [1]. Diabetic retinopathy is a disease of public health importance in Nigeria as it...See sweet to C-suite: Carrie MacEwen
The business world tells us, “Know your why.” But increasingly, we live in a society where people think, “Why bother?” In this interview, David wants to know what makes Carrie MacEwen tick, and why she bothered to get involved locally,...OOC Annual Congress 2026
109th Oxford Ophthalmological Congress
HLA-B27 anterior uveitis
HLA-B27 has previously been shown to have an association with uveitis, ankylosing spondylitis, reactive arthritis, ulcerative colitis and psoriasis. The authors of this review provide an update of the epidemiology of HLA-B27 associated ocular disorders. There is great variation amongst...
Unique case of steroid-induced intraocular pressure spike causing NAION
The literature describes previous cases of nonarteritic anterior ischaemic optic neuropathy (NAION) following rapid rises in intraocular pressure (IOP) leading to reduced optic nerve head perfusion and disruption. This is commonly following ophthalmic procedures, acute glaucoma or steroid eye drops....
Improving distance stereopsis in intermittent exotropia with training
This study compared the control ability of patients with stereopsis and analysed the influencing factors of the improvement of distance stereopsis in children with intermittent exotropia. Seventy-eight children were recruited: 33 male, 45 female with mean age of 8.4 ±2.72...
Comparing bimedial rectus recession and botulinum toxin for partially accommodative esotropia
The authors present a retrospective case review to compare bimedial rectus recession and botulinum toxin injection to the medial recti. This study was possible due to the different first-line preferences of the individual surgeons within the team. Inclusion criteria were...
Pilot trial of Fluoxetine for post-stroke homonymous hemianopia
The authors present a pilot randomised placebo controlled double blind trial assessing 20mg fluoxetine once daily for 90 days versus placebo in stroke survivors with isolated homonymous hemianopia. Exclusion criteria were extensive in terms of pre-existing ophthalmic or neurologic disease,...
Comparison of paediatric migraine and healthy controls using optical coherence tomography angiography
The authors present a cross-sectional study which recruited patients with paediatric migraine without aura along with age and sex-matched healthy controls. Both groups were recruited following attendance to an ophthalmology outpatient clinic. Children diagnosed with any of the following were...
Predicting outcome for visual acuity in optic neuritis associated with multiple sclerosis
The authors present a retrospective cohort study to evaluate key predictors of long-term high-contrast visual acuity following optic neuritis associated with multiple sclerosis. All patients coded as optic neuropathy and assessed by a neuro-ophthalmologist over a 10-year period were screened...
