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In this single-centre retrospective cohort study, the data of pseudoexfoliation (PXF) patients undergoing phacoemulsification cataract surgery from January 2010 to December 2019 was analysed in the National Health Service setting. The study comprised 23,329 eyes of 15,257 patients. Patients with a history of ocular trauma, those undergoing combined intraocular surgeries, and those with missing follow-up data were excluded. The 280 patients in the PXF group had a shorter axial length and shallower anterior chamber depth. The PXF group had a higher prevalence of other ocular copathologies and multiple copathologies. Patients with PXF accounted for 1.2% of the total cohort; identical to the UK National Ophthalmology Database. The authors found that the posterior capsular rupture rate was not increased in the PXF group. There was a higher risk for IOL subluxation, corneal oedema and uveitis. Eyes with PXF had significantly worse postoperative visual acuity (VA) and were less likely to achieve a good visual outcome of logMAR ≤ 0.3. Despite that, the mean improvement in vision was comparable with that of non-PXF eyes. Findings of this study should help counsel patients with PXF. 

Outcomes of cataract surgery in pseudoexfoliation syndrome in England: 10-year retrospective cohort study.
Ong A, Shalchi Z.
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Mahmoud Ahmed

Royal Liverpool University Hospital, UK.

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