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2606 results found

Rituximab efficacy for juvenile idiopathic arthritis

This is a retrospective study about the long-term efficacy of rituximab in patients with severe juvenile idiopathic arthritis (JIA)-associated uveitis. A total of eight patients (15 eyes) were recruited in this study in a single tertiary referral centre from Italy....

Analysis of risk factors for intraocular pressure rise following insertion of fluocinolone acetonide injection in uveitic patients

For this study, the authors analysed the pooled data from three phase2b / 3 multi-centre randomised controlled trials carried out over three years. Included patients had undergone at least one of the following treatments: 1) systemic therapy (corticosteroid / immunosuppressant...

Can coenzyme Q10 have a protective role in ethambutol-induced retinal ganglion cell toxicity

Tuberculosis (TB) is one of the most prevalent infectious diseases, especially in developing or low- income countries. Ethambutol is a widely used drug to treat TB. Ethambutol can cause visual disturbance including ethambutol toxic optic neuropathy (ETON). ETON is one...

Pilot trial of Fluoxetine for post-stroke homonymous hemianopia

The authors present a pilot randomised placebo controlled double blind trial assessing 20mg fluoxetine once daily for 90 days versus placebo in stroke survivors with isolated homonymous hemianopia. Exclusion criteria were extensive in terms of pre-existing ophthalmic or neurologic disease,...

Comparison of motor and sensory outcomes for nonaccommodative esotropia and partial accommodative esotropia

Motor and sensory outcomes of surgery are compared for partial accommodative refractive esotropia (pARET) and acute nonaccommodative comitant esotropia (ANAET) to evaluate factors affecting their surgical success. This was a retrospective study of 38 ANAET (26 males, 12 females) and...

Use of multimodal imaging in diagnosis and treatment planning of traumatic incomplete muscle laceration

This paper discusses details of incomplete rectus muscle lacerations and the unique role of multimodal (local anterior segment optical coherence tomography (ASOCT) and orbital CT/MRI) imaging techniques in the repair of such injuries. This was a retrospective analysis of traumatic...

Addressing diabetes-related complications in Tanzania and Eswatini: A comprehensive approach to eye and foot screening

Diabetes is rising globally, particularly in low- to middle-income countries (LMICs), where healthcare systems are under resourced [1,2]. Among its complications, diabetic retinopathy (DR) and diabetic foot disease are preventable yet frequently overlooked [3-6]. These problems often develop together due...

The future of SLT?

For Feb/Mar 2024, we are looking at a recently released laser machine to perform direct SLT – selective laser trabeculoplasty (DSLT). Although SLT is well known, DSLT is sufficiently novel that a brief description is a good place to start....

Retinoblastoma management update (part 2): treatment, screening and surveillance, long-term follow-up and new developments

Retinoblastoma treatment requires significant multidisciplinary input, but early detection through raising awareness remains key to improving outcomes. In the second article of a two-part series, Manoj Parulekar discusses retinoblastoma management, screening and research. This article has been published in two...

Diagnosis and management of IV cranial nerve palsy

Aetiology: Trochlear nerve palsy can be divided into acute or congenital. Congenital trochlear nerve palsy is usually noted in childhood with development of abnormal head posture. Various pathologies can lead to acute IV nerve palsy, most commonly trauma. Other causes...

Ocular Trauma Scores in paediatric open globe injuries

This is a retrospective case series of 71 open globe injuries in children of less than 18 years of age, with a minimum follow-up period of one year, between 1 September 1992 to 31 July 2011, from the Eye Department...

Moxifloxacin 0.5% for bacterial keratitis

The authors report on the results of a randomised controlled trial comparing commercially available non-preserved moxifloxacin 0.5% vs. a combination of fortified cefazolin 5% and tobramycin 1.3% in the treatment of moderate bacterial keratitis without perforation. Corneal scrapings were collected...