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1525 results found

The global burden of age-related macular degeneration

Age-related macular degeneration (AMD) is the third leading cause of blindness (behind cataract and refractive error). The authors present the results of the Global Burden of Disease (GBD) 2015 study, which included 195 countries. The disability-adjusted life years (DALY) due...

Age-related macular degeneration in elderly persons in Germany

The authors present the findings of a cross-sectional study in 11 seniors’ community centres. Eleven community centres were screened with a total of 281 participants. A third of participants with gradable images were in normal retinal health (32%).The most common...

How accurate is the supplement content in both generic and branded ophthalmology supplements?

This prospective cross-section study compared the concentrations of Vitamin C, Vitamin E, Zinc, and Copper in five dietary supplements including both national and regional brands used for macular degeneration in the United States. They performed a comparative analysis using gas...

Characteristics of Charles Bonnet syndrome in patients with neovascular AMD

This retrospective cross-sectional study aimed to characterise various aspects of Charles Bonnet syndrome hallucinations among patients with neovascular age-related macular degeneration (AMD). Five hundred and ten consecutive patients were asked a screening question to determine if they had ever suffered...

Effect of blue-light filtering intraocular lenses on age-related macular degeneration

This is a retrospective cohort study evaluating whether blue-light filtering (BLF) intraocular lenses (IOL) offer prophylaxis for neovascular age-related macular degeneration (nAMD). The study included 11,397 eyes of 11,397 patients with a mean age of 75.4 ±8.3 years that underwent...

Brolucizumab in age-related macular degeneration, HAWK Study

The aim of the study was to collect additional data on efficacy and safety of brolucizumab 6mg intended for commercialization in age-related macular degeneration (AMD) (with an increase in pH and decrease in polysorbate concentration). The HAWK Study was a...

Macular pigment in relatives of AMD patients

Blue light causes photo-oxidative retinal injury and macular pigment (MP), with lutein, zeaxanthin and mesozeaxanthin as the main components, as a filter that protects the macula from this damage. Previous studies indicated that low levels of macular pigment optical density...

Transsynaptic retrograde degeneration linked to homonymous visual field loss after stroke

centre, of individuals identified with homonymous visual field loss post ischaemic stroke. Exclusion criteria were bilateral ischaemia, anterior / pregeniculate visual pathway affected and other pathology with the potential to effect visual fields. The following were extracted from the medical...

Anti-VEGF injections and macular atrophy progression in patients with nAMD in remission

This is a retrospective study of 59 eyes with neovascuar age-related macular degeneration (nAMD) with at least 6-month remission, to determine the effect of continuing anti-VEGF injections on the progression of macular atrophy (MA) during remission of nAMD. Group 1...

Conjunctivochalasis and aqueous tear deficiency – which one causes symptoms?

This review sought to determine whether conjunctivochalasis (CCh) obliterates the fornix tear reservoir and thus mimics aqueous tear deficiency (ATD). Patients were divided into two groups, with aqueous tear deficiency (CCh +ATD) or without (CCh –ATD), based on results of...

Restoration of colour perception in patients with retinitis pigmentosa

This is a case series testing the feasibility of using bioelectronic retinal prostheses to partially restore colour perception in seven patients with advanced retinitis pigmentosa. Bioelectronic retinal prostheses are able to bypass degenerated photoreceptors to directly stimulate the inner retinal...

Association between neurodegeneration and macular perfusion in the progression of diabetic retinopathy

In this prospective three-year longitudinal study, the authors aimed to explore the relation between retinal neurodegenerative changes and vessel closure (VC) in individuals with non-proliferative diabetic retinopathy (NPDR). The participants included 74 individuals with type 2 diabetes, NPDR, and Early...