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Low dose steroids for ocular dry eye disease in graft vs. host disease
This double-masked randomised clinical trial compared the response of dry eye disease (DED) to treatment with topical steroids in patients with and without graft vs. host disease (GVHD). Forty-two patients in a single centre (n=21 with and n=21 without GVHD)...
Characteristics of bilateral retinal detachment
This was a retrospective study based at a tertiary centre which analysed the specific characteristics of bilateral Rhegmatogeous detachment, taken from the review notes of 300 patients (600 eyes) who had bilateral retinal detachment (RD) surgery between January 2005 and...
Randomised controlled trial of Tecnis intraocular lenses for paediatric cataract
This was a prospective randomised study comparing visual acuity (at distance, intermediate and near), depth of focus and quality of vision in paediatric patients undergoing cataract surgery with implantation of a new monofocal Tecnis Eyhance ICB00 intraocular lens (IOL) vs...More sensitive visual acuity test for age-related macular degeneration
Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. Primarily associated with ageing, genetic factors and lifestyle choices such as smoking also play a contributory role. Patients with early AMD, characterised by the development of...
App detection of leukocoria
This paper outlines ARCELE – Computer Assisted Detection of Leukocoria. This is an iPhone app developed to increase early detection of retinoblastoma by detecting leukocoria. The aim of this study was to determine the use of CRADLE as a screening...The bionic eye – behind the headlines
Multiple visual prosthetic projects and other vision regeneration initiatives being tested in preclinical and clinical development worldwide illustrate continuing progress and opportunities in addressing profound blindness from hereditary retinal diseases and other causes (Table 1). Three implantable bionic vision systems...Genetic profiling for personalised healthcare solutions in AMD – an update
Age-related macular degeneration (AMD) is a multifactorial condition influenced by genetics and lifestyle factors (Table 1). This article outlines several recent advances in AMD genetics, as well as evolving therapeutic concepts and established practical measures for the treatment and /...Stem cell therapy for Parkinson’s disease: researching for an effective cure
Neurodegenerative diseases are characterised by the chronic and progressive loss of neurons, which in turn results in loss of cognitive and physical functions. The World Health Organization has estimated that the disability-adjusted life years lost from neurological disease was about...Insects, swelling and sight loss: a case of orbital inflammatory syndrome
Despite being the most common cause of painful orbital mass in adults and the third most common orbital disease, orbital inflammatory syndrome still proves to be a difficult ocular condition to diagnose, treat, and manage. A 41-year-old lady presented to...Toxoplasmosis and the associated retinochoroiditis: important facts and when to treat
Annie SeeWah Tung provides an overview of toxoplasmosis retinochoroiditis, including guidance on which cases should be treated and the treatment options. Toxoplasmosis retinochoroiditis is an infectious condition that is characterised by retinochoroidal lesions commonly in the posterior pole and is...Case series of toxic anterior segment syndrome
Herein we report two cases of toxic anterior segment syndrome (TASS) following uneventful cataract surgery. Both patients presented 24 hours after their uneventful operations with painless blurred vision in the operated eye. The inflammatory reaction was controlled successfully with an...
