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4217 results found

Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity

Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...

Study calls for thorough investigation of patients with early signs of retinal vascular disease

Patients with the eye condition Paracentral Acute Middle Maculopathy (PAMM) would benefit from further investigation, as their risk of heart attacks and strokes may be greater than previously shown, suggests a new study led by researchers at Moorfields Eye Hospital NHS Foundation Trust.

Spontaneous resolution of inferior oblique over action

The purpose of this study was to evaluate the course of over-elevation in adduction in patients who had surgery for esotropia. Following a chart review, 28 patients met the inclusion criteria with a mean age of 53.5±53.7 months (12-252 months)....

Spontaneous resolution of inferior oblique overaction

The purpose of this study was to evaluate the course of over-elevation in adduction in patients who had surgery for esotropia. Following a chart review, 28 patients met the inclusion criteria with a mean age of 53.5±53.7 months (12-252 months)....

Systemic rituximab immunotherapy in the management of primary ocular adnexal lymphoma single institutional experience

Ocular adnexal lymphomas constitute 2% of all non-Hodgkin’s disease and 5-15% of all extranodal lymphomas and are usually localised, low-grade and of B-cell origin. This opens them up to potential treatment with a systemic monoclonal antibody-based drug (rituximab) directed at...

Refractive changes over time for fully accom esotropia

The purpose of this study was to determine refractive error changes across time and to define factors contributing to decompensation in patients with fully accomodative esotropia (FAET). This was a retrospective study of 223 patients with a mean age at...

Glaucoma surgery in Sturge-Weber syndrome

The authors report the largest retrospective study of surgical results of goniotomoy and trabeculectomy for 42 patients (46 eyes) with glaucoma associated with Sturge-Weber syndrome (SWS). There were 18 males and 24 females, and 62 goniotomy procedures (51 goniotomy surgery,...

Sebaceous gland carcinoma

This is a review of 241 patients diagnosed with periocular sebaceous gland carcinoma which investigates whether age at presentation influences either the clinical presentation or the outcomes of treatment. Twelve percent of patients were classified as young (<40 years old),...

Long-term outcomes after acute primary angle closure

This is a retrospective observational study including 121 eyes of 117 consecutive patients with acute primary angle closure (APAC) over a four-year period, between 1 January 2010 to 31 December 2014. Seventy-three percent had achieved visual acuities of ≥ 6/12,...

App detection of leukocoria

This paper outlines ARCELE – Computer Assisted Detection of Leukocoria. This is an iPhone app developed to increase early detection of retinoblastoma by detecting leukocoria. The aim of this study was to determine the use of CRADLE as a screening...

More sensitive visual acuity test for age-related macular degeneration

Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. Primarily associated with ageing, genetic factors and lifestyle choices such as smoking also play a contributory role. Patients with early AMD, characterised by the development of...

Stem cell therapy for Parkinson’s disease: researching for an 
effective cure

Neurodegenerative diseases are characterised by the chronic and progressive loss of neurons, which in turn results in loss of cognitive and physical functions. The World Health Organization has estimated that the disability-adjusted life years lost from neurological disease was about...