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Rare eye diseases: progress continues with authorised orphan medicines and breakthrough technologies

An update on the development of orphan medicines, recent regulatory treatment approvals for rare eye conditions and advances in retinal prosthetic technologies for blinding diseases. The prevalence of a rare disease is based usually on a range of estimates and...

Diabetes macular oedema in pregnancy self-resolving postpartum

*Equally contributing co-first authors. Diabetic macular oedema (DMO) is a common clinical presentation to ophthalmology clinics. Ample evidence exists for management of DMO in non-pregnant patients. However, there is a paucity of evidence on the optimal management of DMO in...

Mindfulness and cataract surgery experience in ophthalmology doctors in training

Mindfulness can be described as the state in which one is to be fully present in the moment, which draws parallels with surgery. The origins of mindfulness stem from ancient Buddhist traditions, and its utilisation in recent times in the...

A semi-automated algorithm for identifying glaucoma patients with blindness

Patients with sight impairment (previously referred to as partial sightedness) or severe sight impairment (previously referred to as blindness) are eligible for a certificate of visual impairment (CVI). Certification confers eligibility for a wide range of benefits administered by local...

Building data infrastructure for eye research in the NHS: Real-world lessons from the Liverpool Eye Data Platform

The Liverpool Eye Data Platform demonstrates how governance-compliant infrastructure can bring together routinely-collected, siloed NHS eye data. Routine care delivered across the NHS generates vast amounts of clinical data within a healthcare system that is uniquely characterised by comprehensive population...

Ultrasound imaging of the eyes

Since its initial use in the eyes fifty years ago, ultrasound has established itself as a common diagnostic technique in ophthalmology. Sonographers, engineers and clinicians from all around the world have contributed to the development of ocular ultrasonography. As a...

Obituary: Sohan Singh Hayreh (1927 - 2022)

Sohan would have been 95 on 6 November this year, but due to complications of COVID-19, he passed away on 29 September.

Genetic therapy gives infants life-changing improvements in sight

Four young children have gained life-changing improvements in sight following treatment with a pioneering new genetic medicine through Moorfields Eye Hospital and UCL Institute of Ophthalmology, with the support of MeiraGTx. The children were born with a severe impairment to...

Acanthaemoeba keratitis

In the second of this series I describe a case of Acanthaemoeba keratitis (AK) that was misdiagnosed for a prolonged period which resulted in a devastating outcome. This is one of half a dozen similar medico-legal cases I have dealt...

Ocular Dirofilariasis: a diagnosis on the rise?

Dirofilaria repens is one of 40 species of Dirofilaria. It is a zoonotic filarial nematode that commonly impacts dogs, however, human infection can occur through affected organs like skin, lung and eyes [1]. Although, there have been case reports of...

OXSIGHT Onyx – A sight-enhancing wearable

The Onyx is a newly-released (late 2021) wearable with a powered magnifier to assist those with central vision impairment. Unlike the previously covered wearable devices, this enhances existing sight. The unit can either be held against the eyes when needed,...

Intraocular lens technology to deliver enhanced optical performance after cataract refractive surgery

Modern cataract surgery aims to provide patients with the best possible visual outcome with the least dependence on spectacles and minimal or no complications and to treat both cataract and refractive errors with a single procedure. Phacoemulsification is the standard...