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CHARGE syndrome features

CHARGE syndrome (CS) includes coloboma, heart defects, atresia of the choanae, retardation of growth and development, genital and urinary anomalies and ear anomalies. The authors developed an original self-administered questionnaire (VISIOcharge) for patients with CS and used it to evaluate...

Quarter DMEK

This case report describes a novel technique where one quarter of Descemet’s membrane (DM) was transplanted during a quarter-descemet membrane endothelial keratoplasty (DMEK) procedure. DMEK graft was prepared from a 58-year-old corneo-scleral donor after one week in culture. Peripheral DM...

Micropulse vs. continuous wave trans scleral diode cyclophotocoagulation in refractory glaucoma

Continuous wave cyclophotocoagulation (CWCPC) delivers continuous high intensity energy to the ciliary body in an attempt to reduce aqueous secretion and hence lower IOP. It is often used as a treatment of last resort due to the potential side-effects of...

Accelerated (9mW/cm2) corneal collagen cross-linking for keratoconus

This is one of many studies published / to be published on corneal collagen cross-linking that has a treatment time of 10 minutes compared to the previous Dresden protocol of 30 minutes to halt progression of keratoconus. Much has changed...

Changes in refractive error in patients with accommodative esotropia after being weaned from hyperopic correction

This is a retrospective review of medical records of 47 patients with refractive ocular accommodative esotropia who achieved emmetropisation and orthotropia without hyperopic glasses correction and were followed up for at least three years. The objective of the study is...

Long-term effect of gene therapy on Leber’s congenital amaurosis

After reporting the first successful gene therapy results for RPE65 deficiency in three patients in a brief report in 2008, the same team from London now report the results of 12 patients followed up for three years after transfection. As...

RPE tears in cases of IPCV

The aim of this study was to investigate the occurrence, characteristics, management and prognosis of retinal pigment epithelium (RPE) tears in patients with polypoidal choroidal vasculopathy (PCV). Medical records of previous cases were reviewed over an eight-year period from a...

Conservative surgical management of optic disc pit maculopathy

Four cases are presented in this case report that illustrates the option of conservative surgical management for optic disc pit complicated by maculopathy (ODP-M). Four men aged 24-67-years-old with no spontaneous resolution of ODP-M for a minimum of three months,...

Effect of long-term scleral contact lenses on corneal topography, tear film and impression cytology in keratoconus

This study of 16 keratoconus patients aimed to investigate the impact of long-term scleral contact lens (ScCL) wear on corneal curvature, corneal thickness, tear film function and ocular surface in patients with keratoconus. Corneal topography, tear osmolarity test, Schirmer 1...

Could idebenone by the solution for treating dominant optic atrophy?

Dominant optic atrophy (DOA) is a disease of the retinal ganglion cells, with no current treatment options. In most cases, DOA is caused by a mutation in the OPA1 gene. The aim of this study was to evaluate the effect...