This is a radiological study of the volume of the sphenoid trigone in normal subjects. The authors were interested to see how much volume could be gained by removal of the trigone during an orbital decompression for thyroid eye disease....
The authors aimed to determine the current clinical practice of atropine penalisation (AP) in the UK, to identify perceived barriers limiting use of AP as a first line treatment and ascertain whether any of the barriers could be resolved. An...
This study investigated the influence of nicotine in an experimentally induced diabetic rat model. They used non-invasive high-resolution spectral domain optical coherence tomography (SD-OCT) imaging to provide quantitative information on the temporal alterations of retinal structures at the micrometer resolution...
The purpose of the study was to evaluate the effect of intravenous mannitol 20% on intraocular pressure in vitrectomised silicone-oil filled eyes. A prospective analysis of consecutive patients was undertaken with their fellow eyes taken as controls. Thirty-one patients were...
The purpose of this retrospective study from two tertiary Institutions in Israel over a period of 13 years, is to present the long-term outcomes of uveitic glaucoma and to identify risk factors for progression. The study included 34 patients (53...
Functional visual field loss is traditionally assessed by kinetic perimetry, typically producing spiralling isopters. This study looked at the spatial distributions of functional field deficits using automated static perimetry. A retrospective review of automated perimetry records was conducted using a...
Ocular Ischaemic syndrome is a devastating eye disease caused by severe carotid stenosis. This study’s purpose was to develop a reliable rat model for this syndrome by subjecting rats to common carotid artery occlusion and sham surgery. Rats were assigned...
Fluorescein angiography (FA) and spectral-domain optical coherence tomography (OCT) are the most common examinations used in the management of anti-VEGF therapy in choroidal neovascularisation (CNV). In comparison to FA, OCT provides a noninvasive evaluation of the macula. Myopic CNV are...
Traditional teaching has held the best scars are achieved with cold steel although no previous study has formally investigated this hypothesis in oculoplastic surgery. This paper describes a non-randomised cross-sectional study comparing the scar quality achieved from cold steel with...
MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...
This is an immunohistochemical study looking at variation in the expression of the programmed death-1 receptor (PD-1) and the programmed cell death ligand-1 (PD-L1), comparing cutaneous malignancies which invaded the orbit with uncomplicated nodular basal cell carcinomas. The authors retrospectively...
This prospective study investigated the ocular surface temperature in patients with pterygia compared to those with dry and healthy eyes respectively. Previous studies have shown that patients with dry eyes show a significant decrease in ocular surface temperature on sustained...