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γδ T cell depletion does not affect fungal keratitis
1 August 2015
| Graham Wallace
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EYE - Cornea, EYE - General
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CFW, Cytokines, FK, Fungal keratitis, IL-17, Neutrophils, calcofluor WHITE, fungal keratitis, γδ T cells
Fungal keratitis (FK) is a blinding condition prevalent in agricultural areas of countries such as India and China. The fungus enters the cornea and induces an inflammatory response which leads to tissue damage. Neutrophils are the earliest infiltrating immune cells...
Effective management of dry eye and ocular surface disease
4 August 2021
| Rod McNeil
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EYE - General
Experts recommend a consistent approach to diagnosis, therapeutic targeting by disease subtype and escalation of therapy when tear substitutes are not sufficient. Experts call for a consistent, unified approach to diagnosis of dry eye disease (DED), with a new simple...
Patients blinded by stem cells! How safe are they really?
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Patients blinded by stem cells! How safe are they really? Ever since the successful results following...Triamcinolone (TA) deposits following subcutaneous injection to treat chalazion
2 August 2022
| Muhammad Adil Seelarbokus, Edward Foo, Jennifer HY Tan
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EYE - Oculoplastic, EYE - General
Chalazia are chronic lipogranulomatous inflammations of the eyelid secondary to a blocked meibomian gland. Whilst most resolve spontaneously, certain chalazia warrant treatment. Options include incision and curettage (I&C), lesion excision, intralesional steroid injections, and botox injections [1]. I&C is usually...
Resurfacing the ocular surface
1 April 2016
| Harminder Dua (Prof)
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EYE - Cornea
The ocular surface (OS) is an anatomical and functional unit made of the tear film, the conjunctival, limbal and corneal epithelium, the lacrimal, mucous and meibomian glands and the lids and blink reflex. The tear film is composed of a...
My ophthalmic elective: focusing on myopia in Taiwan
The authors describe their elective experience and delve further into high myopia, an emerging ophthalmic disease that is increasingly recognised in and outside Asia. The medical school elective programme presents an opportunity for students to conduct learning in their chosen...Periocular burns: a literature review of classification, management protocols and outcomes of treatment
The author provides a review of the current literature regarding the principles of classification, management protocols of acute ocular and periocular burns and the role of the burn and oculoplastic surgeon involved in their care. More than two-thirds of facial...Q&A: Mr Goel and Mr Loomba on alcohol delamination and phototherapeutic keratectomy (PTK) for the treatment of recurrent corneal erosion syndrome
14 June 2023
| Aina Pons, Abhinav Loomba, Siddharth Goel
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EYE - Cornea
Recurrent corneal erosion syndrome is a common, recurrent condition caused by abnormal epithelial adhesion to the underlying basal lamina. Spontaneous breakdown of the corneal epithelium can lead to the sudden onset of ocular pain, blurred vision, tearing and photophobia, typically...
Survey reveals poor public awareness of dry eye disease
17 May 2021
A new survey has revealed how few people are aware of Dry Eye Disease, a debilitating and painful eye condition which affects one in four people in the UK.
Corneal keloid: Report of natural history and Outcome of Surgical Management in Two Cases
Corneal keloids are rare and typically reported following trauma (including post-surgical) and has been reported without any trauma or previous surgery. A corneal keloid differs from a hypertrophied scar in that it occurs months/years after the injury, enlarges over time...
Long-term meibomian gland function following a single thermal pulsation treatment
1 December 2013
| Kwesi Amissah-Arthur
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EYE - Cornea, EYE - General
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LipiFlow thermal pulsation system, dry eye, meibomian gland dysfunction
Dry eyes secondary to blepharitis and or meibomian gland dysfunction, though extremely common, is an annoyingly difficult condition to treat for several patients. Part of this difficulty lies in the inability of most patients to follow intensive and often times...
Culture positivity of needles for IVT injections
1 December 2013
| Saruban Pasu
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EYE - Vitreo-Retinal
Given the worldwide use of intravitreal (IVT) injections, the authors of this paper set out to evaluate the rate of culture positivity of the needles used in routine IVT injections and compare this positivity between 27-gauge and 30-gauge needle tips....
