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Autophagy in lens mitochondria loss
The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...
Corneal neurotisation with an allograft
This is the first reported use of an acellular nerve allograft for corneal neurotisation. Seven patients received a 7cm long commercially prepared acellular nerve allograft. This was coapted to a functioning supratrochlear, supraorbital or infraorbital nerve and then tunnelled to...Quiz Feb/Mar 2020
History A 92-year-old female patient was referred for a three-month history of a left conjunctival growth with ocular irritation. Her past medical history included: hypertension, back pain and osteoarthritis, all of which were controlled by medication. On examination: vision in...The ophthalmologist’s elbow: a potentially painful point of contact
Three months ago I leant, in the customary manner, on the box of my indirect lens at the slit lamp to examine a patient’s fundus. An acute and severe pain in the tip of my elbow immediately interrupted me. I...Conference Report: UCL Institute of Ophthalmology Summer School 2025
The UCL Institute of Ophthalmology Summer School 2025 was held in collaboration with Moorfields Eye Hospital run by Gordon Hay and Tara Bader. This was a comprehensive five-day course attended by medical students and resident doctors from around the world....Acute macular neuroretinopathy
Acute macular neuroretinopathy (AMN) is a rare condition that typically affects young women and presents with photopsia and paracentral scotomata [1]. We describe a case of severe acute macular neuroretinopathy, following Covid-19 infection. A 30-year-old woman presented to the urgent...A complicated case of cytomegalovirus viremia: “What would you do doctor?”
Mrs W walked gracefully into my urgent care clinic. It was another busy session and I hoped she did not have anything serious going on which might slow the clinic further. She was an elegant 72-year-old lady who seemed like...
Self refracting – child’s play?
Uncorrected refractive error was the leading cause of vision impairment in the world in 2010. Although refractive error may be safely and effectively corrected with spectacles, lack of well-trained refractionists in settings of limited resources may be a major barrier....
Clinical outcomes of endoscopic dacryocystorhinostomy
The aim of this study was to report the authors’ experience with endoscopic dacryocystorhinostomy (ED) in a paediatric population and to evaluate the effect of surgical site reassessment on anatomy and clinical outcomes. The study included 47 children <18 years...How to pass the Refraction Certificate
Unfortunately, I had the pleasure of getting to know this exam intimately. With adequate preparation this does not have to be the case for most people. The exam has recently changed to consist of 10 OSCE style stations (previously 12)....
