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Handbook of Pediatric Retinal OCT and the Eye-Brain Connection

Paediatric optical coherence tomography (OCT) imaging of the eye remains an evolving technology to date. This handbook delves into this challenging area successfully and gives a comprehensive and detailed input into paediatric OCT pertaining to the retina and the optic...

Ophthalmology Lecture Notes (Twelfth Edition)

During medical school, our seniors often told us that the easiest way to remember something is to understand it. And rightly so, when I came across the Ophthalmology Lecture Notes textbook as a student I realised that the key to...

OCT in proliferative diabetic retinopathy

This report set out to describe the anatomical relationships between retinal neovascular complexes (NVC), the posterior vitreous, and the vitreoretinal interface in patients with proliferative diabetic retinopathy using spectral domain OCT. The following was recorded for each NVC 1) posterior...

Retreatment of myopic LASIK with femtosecond and custom ablation

The purpose of this study was to identify the risk factors for retreatment post laser in situ keratomileusis (LASIK). A retrospective chart review was carried out for a four-year period and all patients who had undergone LASIK at the Boston...

Natural regression of brow heaviness in thyroid eye disease

This is a retrospective review of the change over time in the sub-brow fat volume in 104 patients with thyroid eye disease. Standardised photographs taken at diagnosis were compared with those taken after an average period of 10 years (+/-...

Transcriptomic analysis of ocular tissues

Transcriptomics is defined as the analysis of the complete set of RNA transcripts present in a cell under different circumstances, quiescent versus challenge, by microarray analysis. Comparison of transcriptomes identifies genes that are differentially expressed in different cell populations under...

Automated grading of diabetic retinopathy: is it possible?

Diabetic retinopathy (DR) is a frequent microvascular complication of diabetes and a leading cause of blindness worldwide. However, much of this diabetic blindness can be delayed or even prevented with timely diagnosis and proper treatment. For this reason, regular screening...

Prostaglandin levels in femto cataract surgery

Following previous reports of pupil size decrease after femtosecond treatment, the authors compare levels of prostaglandins in patients undergoing femtosecond assisted cataract surgery with those having routine cataract surgery. Patients with inflammatory eye disease, previous trauma surgery, age-related macular degeneration...

Macular atrophy with aflibercept

The authors of this paper set out to investigate the prevalence of macular atrophy in treatment-naive patients with neovascular AMD undergoing aflibercept monotherapy (three monthly loading injections followed by subsequent treatment every two months). Case notes over a three year...

Relationship between nocturnal intraocular pressure elevation and diurnal intraocular pressure level in NTG patients

This group studies Korean normo-tension glaucoma (NTG) patients over a 24-hour period to assess if there was a relationship between nocturnal intraocular pressure (IOP) and diurnal IOP. They have previously suggested differences in diurnal IOP may have varying mechanisms of...

Results of four years of implantation of XEN glaucoma gel stent

This multi-centred prospective, non-randomised study presents the long-term clinical outcomes in patients after implantation of transscleral XEN Glaucoma Gel Microstent, 63μm. (XEN-GGM, Allergan, New Jersey). It was conducted in Austria, Canada and Germany. Sixty-four consecutive eyes of 64 patients with...

Retinal ischaemia on OCTA and diabetic retinopathy grade

The authors quite rightly point out that quantification of retinal ischaemia has the potential to serve as a biomarker for diabetic retinopathy disease progression. They set out to investigate the relationship between area of ischaemia on a swept source OCTA...