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Innovations in posterior uveitis: In conversation with Dr Colin Chu

A research team has been awarded significant funding by the National Institute for Health and Care Research (NIHR) to develop an innovative drug-device combination that aims to revolutionise how individual immune cells are monitored and treated in patients at Moorfields...

Ultra-widefield fundus autofluorescence

The authors assessed the ease and utility of ultra-widefield fundus autofluorescence (UWF-FAF) in detecting suspected inherited retinal disease in children who were difficult to examine. They aimed to assess the sensitivity of UWF-FAF and UWF-CF (colour fundus) photography and clinical...

Normative reference values for optic nerve sheath diameter in children

The purpose of this study was to measure optic nerve sheath diameter (ONSD) in paediatric patients without pathology using brain CT performed for various reasons and to provide normal tomographic reference values. This was a retrospective study of CT scans...

Characteristics of limbal lymphatic vasculature on confocal microscopy

This ex vivo study aims to describe the morphological characteristics of the human limbal lymphatic vasculature using confocal microscopy and immunofluorescence. Twelve corneal specimens are obtained from human donor eyes. These corneal buttons are not suitable for transplantation due to...

Opening the AI ‘black box’ for glaucoma

Artificial intelligence (AI) models show great promise for glaucoma detection using retinal images, but their ‘black box’ nature is a major barrier to clinical adoption. Clinicians are often hesitant to trust a diagnosis without understanding its reasoning. This paper provides...

QR codes in posters

Sometimes it is nice to read a poster you see at a conference in more detail at a later date. With a little effort you can easily distribute a PDF version of your poster to interested readers by ‘attaching’ a...

Assessing everyday visual function in dry AMD – what matters to the person?

Age-related macular degeneration (AMD) is the primary cause of blindness in the developed world and is accountable for more than one half of sight impairment registrations within England and Wales [1]. AMD is prevalent in people aged 60 years and...

The next wave of AI in ophthalmology: From screening to communication

Artificial intelligence (AI) is reshaping ophthalmology, moving from research laboratories into everyday clinical care [1]. With its strong reliance on imaging and pattern recognition, ophthalmology is uniquely positioned to benefit from AI innovations. These developments range from autonomous disease screening...

Imaging within clinical research trials

Clinical research is essential to the future of healthcare and the wellbeing of patients, no matter what health condition they face. Many patients who choose to participate in clinical research studies in ophthalmology find optimism in discovering novel medicines to...

Beware the disc in myopic patients

Glaucoma is a chronic and progressive optic neuropathy characterised by damage of retinal ganglion cells. Evaluation of structural damage of the optic nerve is important in glaucoma diagnosis. The ISNT rule states that the neuroretinal rim width is generally widest...

Optical coherence tomography – reinventing the eye examination

It has been 25 years since Huang et al. presented the first optical coherence tomography (OCT) images in Science [1]. With vast improvements in OCT technology over the years, it is now possible to acquire high-resolution cross-sectional images of the...

The miracle of multi-professional working in modern-day eyecare

"It’s a Tuesday morning, and I’m in the presence of one of the most mind-boggling accomplishments in human history. This thing is so astounding in its complexity and scope, it makes the Panama Canal look like a third grader’s craft...