You searched for "inflammation"
My Top Five: Key insights from recent research into uveitis in adults
Uveitis, characterised by inflammation of the uvea – the eye’s middle layer comprising the iris, ciliary body, and choroid – remains a leading cause of visual impairment worldwide [1]. It primarily affects adults aged 20–50 years. Untreated uveitis may cause...
Ologen Collagen Matrix to treat ocular hypotony after filtration glaucoma surgery
The authors report a retrospective, observational case series of a Japanese cohort. 12 consecutive implantations of ologen in nine eyes of nine subjects (five men, four women; mean age ±SD, 72.1±12.7 years) who underwent subconjunctival implantation of the device to...Like a moth to AC flare: CMV-associated hypertensive anterior uveitis
Hypertensive anterior uveitis can present a diagnostic challenge to clinicians working in emergency eye departments. While prompt initial control of intraocular pressure (IOP) and inflammation is essential, elucidating the underlying aetiology is critical for long-term visual outcomes. When there is...
Topical cyclosporine A 0.05% for recurrent anterior uveitis
This is a retrospective case-crossover study conducted by reviewing medical charts of patients treated for recurrent anterior uveitis between 2002 and 2011 at the Kellogg Eye Centre by one cornea specialist. The demographics, episodes of anterior uveitis, severity of episodes...Typical and atypical optic neuritis – diagnosis and initial management
Optic neuritis is a relatively common presentation to ophthalmologists in the acute setting. The vast majority are cases of ‘typical’ optic neuritis (ON) but a smaller group of conditions, so-called, ‘atypical’ optic neuritides require a different work-up and management strategy....Resurfacing the ocular surface
The ocular surface (OS) is an anatomical and functional unit made of the tear film, the conjunctival, limbal and corneal epithelium, the lacrimal, mucous and meibomian glands and the lids and blink reflex. The tear film is composed of a...Sensitive cilia – eyelashes in health and disease
In health our eyelashes protect the eyes, but in disease they can disfigure, impair quality of life and threaten vision. In this review the authors discuss aspects of lashes that are relevant to all professionals working near the eyes and...
RPE atrophy onset in treated nAMD
In this study the authors aim to evaluate the role of various factors for the development of retinal pigment epithelium (RPE) atrophy over a period of five years in patients with nAMD. Fifty-two newly diagnosed nAMD patients with complete absence...It’s not always GCA
Giant cell arteritis (GCA) is an immune mediated granulomatous inflammatory disease that affects muscular middle or large sized arteries. It is considered as a continuation of polymyalgia rheumatica (PMR) when the severity of the disease has increased. It is the...
Ovarian hormones drive onset of Sjogren’s disease in mice
Sjogren’s syndrome (SS) is a debilitating, sight-threatening, systemic autoimmune disease with no effective treatment available. SS is characterised by lacrimal gland lymphocytic infiltration and epithelial cell death, as well as by the presence of serum autoantibodies. Patients have severe dry...Oct/Nov 2018 Quiz
History A 37-year-old male was referred from the Emergency Eye Clinic with a swollen right upper eyelid. Symptom relieved with nonsteroidal anti-inflammatory drugs (NSAIDs). The initial clinical diagnosis was dacryoadenitis. The patient presented again six weeks later with 3mm proptosis,...
