Journal Reviews archive for 2016
Anterior segment OCT predicts gonioscopic angle closure
This is a prospective observational study of 342 subjects over four years. Sixty-five were controls who had open angles both on gonioscopy and AS-OCT, while 277 had open angles only on gonioscopy but iridotrabecular contact (ITC) on AS-OCT (one to...
RPTP-σ increases pro-MMP activity in a trabecular meshwork cell line following oxidative stress conditions
This study aims to outline the role of phosphatases in the aqueous drainage system by overexpressing receptor tyrosine phosphatase sigma (RPTP-σ) in a human normal trabecular meshwork cell line and describing its effect on subtypes of matrix metalloproteinases (MMP) and...
Amiodarone-associated optic neuropathy
This is a retrospective population-based cohort study to evaluate the risk of developing optic neuropathy from the use of amiodarone in Taiwan. Over a five-year period (2005-2009), there were 6175 amiodarone-treated patients with 24,700 patients taken as controls. After a...
A case report of bidirectional aberrant upward eye movement
The authors present a case report of a 14-year-old boy with left ptosis and strabismus since childhood. In primary position he had left hypotropia with ptosis. On elevation of the right eye, the left eye depresses and adducts. Conversely, on...
A novel computerised portable pupillometer detects and quantifies relative afferent pupillary defect
We have all had referrals from A&E telling us that a patient can’t see out of one eye. Sleepily we may ask “Is there an relative afferent pupillary defect (RAPD)?” to evaluate the seriousness of the presentation. The response is...
A rare case of ophthalmic complications following allergic fungal sinusitis
The authors present an unusual case report of a 32-year-old man with advanced allergic fungal sinusitis, presenting with severe bilateral visual loss and restricted ocular motility. On presentation he had an 18 month history of progressive nasal obstruction, as well...
Placement of an eyelid weight as an upper lid spacer for lagophthalmos
Upper lid loading with a weight is a well described procedure for the treatment of lagophthalmos and exposure keratopathy. The authors describe a modification of this procedure whereby the levator aponeurosis is recessed in combination with supratarsal weight implantation. The...
Comparison of central laminar thickness in optic neuropathy and normal eyes
The study compares central laminar thickness (LT) among patients with glaucomatous optic neuropathy (GON), patients with non-GON and normal subjects. The non-GON group comprised eyes with demyelinating optic neuropathy (ON), anterior ischaemic ON, compressive ON, Leber hereditary ON and traumatic...
Light reflex in preterm infants
In this study, the pupillary size and light reflex was examined in premature infants using infrared video-pupillography and stimuli of red and blue light. Only eyes of infants without retinopathy of prematurity were included in the study. Pupillary light reflexes...
A case report of papilloedema caused by unilateral jugular vein thrombosis
In rare cases, unilateral jugular vein thrombosis can lead to increased intracranial pressure and papilloedema, resulting in headaches and visual loss. The authors describe the case of a 45-year-old patient with squamous cell carcinoma of the larynx who developed right...
Interesting causes and consequences of orbital inflammations
Three articles discuss various causes and consequences or orbital cellulitis. The first highlights the possibility of orbital cellulitis causing cavernous sinus thrombosis and in the case presented progression to internal carotid artery aneurysm. The authors highlight the importance of considering...
Prostaglandin-associated periorbitopathy
This is a masked study of 33 patients who had been taking a prostaglandin analogue in one eye only for at least a year, to look for signs of prostaglandin-associated periorbitopathy (PAP). The investigators devised a new grading system to...
