Journal Reviews

Neuro-Ophthalmology journal cover image

Can coenzyme Q10 have a protective role in ethambutol-induced retinal ganglion cell toxicity

3 April 2023 | | Neuro-Ophthalmology | Ethambutol, coenzyme Q10, ethambutol toxic optic neuropathy, retinal ganglion cells, tuberculosis

Tuberculosis (TB) is one of the most prevalent infectious diseases, especially in developing or low- income countries. Ethambutol is a widely used drug to treat TB. Ethambutol can cause visual disturbance including ethambutol toxic optic neuropathy (ETON). ETON is one...

PD-1 and retinal ganglion cell death

1 February 2016 | | Apoptosis, Large retinal ganglion cells, Neuroprotection, Optic nerve crush, Programmed cell death-1

Death of retinal ganglion cells (RGC) in conditions like glaucoma leads to permanent visual loss. RGC death can be due to the initial stress such as raised intraocular pressure or secondary to mechanism such as oxidative stress. Programmed cell death-1...