Journal Reviews

Use of international interocular difference thresholds for optic neuritis diagnosis in clinical practice

5 June 2023 | | Neuro-Ophthalmology | AQP4, MOG, MOGAD, Multiple sclerosis, NMOSD, optical coherence tomography

Multiple sclerosis (MS) is the most common non-traumatic cause of disability in young people, and visual symptoms can be the initial manifestation in up to 20% of cases. Retinal examination can be helpful in making the correct diagnosis. The latest...

Seminars in Ophthalmology journal cover image

MRI characteristics of NMO, MOG and MS-related ON

3 June 2021 | | Neuro-Ophthalmology | MRI, Optic nerve, multiple sclerosis (MS), myelin oligodendrocyte glycoprotein antibody disease (MOG-AD), neuromyelitis optica (NMO), optic neuritis

This review article examined differences of MRI appearances that can help clinicians assess and manage these important neuro-ophthalmic disorders. It also examined the role of optic nerve MRI as a prognostic indicator in acute optic neuritis (ON). The major findings...

Investigating MOG-IgG as a cause for optic perineuritis

5 August 2020 | | Neuro-Ophthalmology | Optic perineuritis, myelin oligodendrocyte glycoprotein (MOG), aquaporin-4 (AQP4), optic neuritis, optic nerve sheath

Optic perineuritis can be a manifestation of infectious and systemic inflammatory disorders, but in most cases is considered idiopathic. Diagnosis is established by magnetic resonance imaging (MRI) with the demonstration of optic nerve sheath enhancement with sparing of the optic...