Journal Reviews archive for 2025
Treatment for chronic severe bilateral blepharokeratoconjunctivitis
This study evaluated the efficacy and safety of oral azithromycin treatment combined with topical antibiotics and anti-inflammatory agents in paediatric patients with chronic severe bilateral blepharokeratoconjunctivitis (BKC). The authors recruited 29 consecutive patients (58 eyes) with mean age at diagnosis...
Long-term motor and sensory outcomes after surgery for high AC/A ratio esotropia
This study reports the long-term ocular alignment and sensory outcomes after medial rectus recession for high accommodative convergence to accommodation (AC/A) ratio esotropia with a minimum postoperative follow-up of five years. The study included 34 patients (16 male); 31 had...
Appropriateness of online education material for leukocoria
The purpose of this study was to assess the quality, reliability and readability of online patient education materials on leukocoria. A Google search was undertaken for leukocoria and white pupil. They identified and assessed the first 50 sources for both...
How the thinking machine is transforming the retinal landscape
Regulatory approval of the first two therapeutic substances for the management of geographic atrophy (GA) secondary to age-related macular degeneration has been a major breakthrough. The authors explored the issue surrounding the lack of agreed therapeutic standards and diagnostic tools...
Reporting and representation of race and ethnicity in paediatric ophthalmology clinical trials
This systematic review aimed to identify the prevalence and factors associated with the reporting of race / ethnicity data in paediatric ophthalmology studies and how this has changed over time. A systematic search strategy to find randomised controlled trials between...
Saccadic duration and trajectories in monkeys with induced strabismus
This author aimed to (1) determine whether saccadic duration is consistently the same for the two eyes and / or whether the amplitude-duration relationships differ for the two eyes; and (2) test the hypothesis that saccade trajectories show abnormally large...
Long-term treatment for diabetic macular oedema
The authors set out to characterise anti-VEGF treatment patterns and long-term outcomes in patients with diabetic macular oedema. A retrospective analysis of over 190 thousand patients on the Intelligent Research in Sight registry was performed. Of these, 1236 eyes have...
Under pressure: the constant drive to improve IOP monitoring
The authors offer a comprehensive overview of interplay between glaucoma and intraocular pressure (IOP), IOP measurement principles and historical measurement techniques and progress in IOP measurement devices. The authors explore the issues surrounding current thinking in IOP measurement and its...
Efficacy of augmented-dosed surgery versus botulinum toxin A injection for acute acquired concomitant esotropia
This is a retrospective study of 104 patients diagnosed with acute acquired concomitant esotropia (AACE) between 2020 and 2022. Potential factors that influence the dose-response of bilateral medial rectus recession (MRec) and the rate and risk factors for ACCE relapse...
Sirolimus for lymphatic-venous malformation
This is a case report on the use of oral sirolimus in the treatment of lymphatic-venous malformations. This condition can often be sight-threatening when present in the orbit and traditional management options have included observation, sclerotherapy and surgery. Both sclerotherapy...
Amblyopia information provided by chatbots – how readable and understandable is this?
The purpose of this study was to evaluate the understandability, actionability and readability of responses to frequently asked questions about amblyopia provided by ChatGPT-3.5, Bing Chat, Bard and the American Association for Pediatric Ophthalmology and Strabismus (AAPOS) website, along with...
Horizontal recti injection of botulinum toxin for treatment of infantile nystagmus
In this study the authors aimed to demonstrate the effect of botulinum toxin (BT) on the frequency of ocular oscillation in children with infantile nystagmus syndrome (INS). Botulinum toxin was administered with direct injection into the horizontal recti muscles using...
