Vision screening standards for fitness to drive
1 December 2022
| Kurt Spiteri Cornish
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EYE - Vitreo-Retinal
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Big Data, driver vision standards, driving, electronic medical records, vision, visual acuity
Most countries require that vision meets a pre-defined standard in order to be legally permitted to drive, but these standards vary widely. The primary method by which vision is assessed to determine suitability for driving is by measuring visual acuity...
Practice patterns in managing exogenous endophthalmitis
1 December 2022
| Kurt Spiteri Cornish
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EYE - Vitreo-Retinal
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Global practice patterns, endophthalmitis, exogenous endophthalmitis, ophthalmology
The authors of this study conducted a global survey of medical institutions regarding management of exogenous endophthalmitis to assess current practice patterns for this sight-threatening emergency. Thirty-six (of 42 institutions) responded and were included in the analysis. Results were as...
Distribution, progression, and outcomes of inflammatory chorioretinal lesions
1 December 2022
| Kelvin Cheng
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EYE - Vitreo-Retinal
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Autofluorescence, inflammatory lesions, multifocal choroiditis, multimodal imaging, optical coherence tomography, punctate inner choroidopathy, uveitis
This study investigated the distribution and progression of multifocal choroiditis (MFC) inflammatory lesions in 25 eyes of 20 patients and their correlations with clinical outcomes at 24 months. The distribution of choroiditis inflammatory lesions were evaluated semi-automatically using a dedicated...
Diagnostic and prognostic roles of serum interleukin-6 in patients with uveitis
1 December 2022
| Kelvin Cheng
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EYE - Vitreo-Retinal
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Behçet’s disease, interleukin-6, juvenile idiopathic arthritis, rheumatoid arthritis, systemic lupus erythematosus, uveitis
This is a retrospective observational case series investigating the diagnostic and prognostic role of serum interleukin (IL)-6 in patients with uveitis involving 80 patients – 60 patients (75%) with normal IL-6 levels and 20 patients (25%) with high IL-6 levels....
Chorioretinal atrophy in punctate inner choroidopathy / multifocal choroiditis
1 December 2022
| Kelvin Cheng
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EYE - Vitreo-Retinal
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Chorioretinal atrophy, long-term outcome, multifocal choroiditis, punctate inner choroidopathy, white dots syndrome
This study reported the five-year outcomes of chorioretinal atrophy (CRA) progression in patients with punctate inner choroidopathy (PIC) or multifocal choroiditis (MFC) in 45 eyes of 36 patients. The mean age of the cohort of patients was 37 ±13.37 years...
Retrospective review of visual outcomes in Idiopathic intracranial hypertension (IIH)
1 December 2022
| Claire Howard
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EYE - Neuro-ophthalmology
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Idiopathic intracranial hypertension, Pseudotumor cerebri, visual outcome
Idiopathic intracranial hypertension (IIH) is a clinical syndrome characterised by headache and papilloedema that can lead to significant visual morbidity. IIH is diagnosed by the modified Dandy criteria, which include normal neuroimaging and cerebrospinal fluid (CSF) composition, high CSF opening...
Does religious fasting affect intraocular pressure or retinal parameters?
1 December 2022
| Claire Howard
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EYE - Neuro-ophthalmology
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Religious fasting, Retina, macula, optical coherence tomography angiography
Nearly one billion Muslims fast every year during the month of Ramadan. Due to the difference between the lunar and solar calendars, religious fasting time can range from 11 to 17 hours per day. This prolonged abstinence from food and...
Do patients with prolactinomas using dopamine agonist drugs have autonomic dysfunction?
1 December 2022
| Claire Howard
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EYE - Neuro-ophthalmology
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Prolactinoma, cabergoline, dopamine, dynamic pupillary response, static pupillary response
This prospective study aimed to determine whether there is autonomic dysfunction in patients with prolactinomas using dopamine agonist (DA) drugs by measuring static and dynamic pupillary responses using an automatic pupillometric device.Included were 25 eyes from 25 patients who were...
Visual prognosis in Irish Leber’s hereditary optic neuropathy
1 December 2022
| Claire Howard
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EYE - Neuro-ophthalmology
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Leber’s hereditary optic neuropathy, idebenone, inherited optic neuropathy, mtDNA, ophthalmic genetics, optic atrophy
Leber’s hereditary optic neuropathy (LHON) is an inherited optic neuropathy This paper presents a retrospective review of clinical data from patients with LHON presenting to an Irish tertiary referral ophthalmic hospital. Clinical and genetic characteristics were assessed for useful biomarkers...
Transient thickening of the macular retinal nerve fibre layer in acute optic neuritis
1 December 2022
| Claire Howard
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EYE - Neuro-ophthalmology
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Optic neuritis, axonal degeneration, neurofilament protein, retina, tissue
Acute optic neuritis (ON) causes axonal degeneration, which can be quantified from the blood by neurofilament protein (Nf) levels. Within about three months, atrophy of the retinal nerve fibre layer (RNFL) follows. However, it remains challenging to explain why there...
Assaying acetylcholine receptor antibodies in the diagnosis of ocular myasthenia
1 December 2022
| Claire Howard
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EYE - Neuro-ophthalmology
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Ocular myasthenia, anti-acetyl choline receptor antibody, generalised myasthenia
Myasthenia gravis (MG) is an autoimmune disease that leads to impaired neuromuscular transmission. Solely ocular manifestations of MG (OMG) occur in 15-50% of cases, most frequently in the form of fluctuating ptosis and diplopia. Most cases of OMG convert later...
Risk factors for visual impairment in facial nerve palsy
Facial nerve palsy (FNP) is known to be associated with corneal exposure due to the nature of the condition, but how many of those will go on to develop severe visual impairment (SVI)? This study investigates the risk factors associated...
