Bromfenac versus betamethasone in diabetic macular oedema
31 October 2023
| Kurt Spiteri Cornish
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EYE - Vitreo-Retinal
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Diabetic macular edema, betamethasone, bromfenac, central subfield thickness, intraocular pressure
This is a randomised, prospective, single-centre trial in patients diagnosed with diabetic macular oedema (DMO) with central subfield thickness (CST) of 250-500µm, who refused anti-VEGF treatment. Nineteen eyes of 19 patients were randomised to bromfenac (BF) or betamethasone (BM) drops,...
Retinal changes prior to hydroxychloroquine toxicity
1 October 2021
| Ed Rule
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EYE - Vitreo-Retinal
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Ganglion cell layer, Hydroxychloroquine, Optical coherence tomography, Retina, Retinal thickness
In this retrospective longitudinal study, the authors examined changes in retinal layer thickness in patients taking hydroxychloroquine without evidence of retinopathy. Patients were drawn from a hydroxychloroquine screening clinic and required at least two OCT scans, at least one year...
Comparison of changes in ECD and CCT between CPS and FLACS
5 June 2020
| Jonathan Chan
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EYE - Cataract, EYE - Refractive
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ECD, FLACS, corneal thickness, endothelial cell density, femtosecond laser, phacoemulsification
This is an intraindividual randomised clinical trial of 134 eyes from 67 patients, one eye was treated with femtosecond laser-assisted cataract surgery (FLACS) (including pretreatment of main incision, side port, capsulotomy and lens fragmentation) and the fellow eye received conventional...
Using OCT to screen and monitor Alzheimer’s disease
1 June 2016
| Claire Howard
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EYE - Neuro-ophthalmology
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Macular thickness, mild cognitive impairment, optical coherence tomography, subjective memory complaints
Alzheimer’s disease (AD) is a neurodegenerative illness characterised by progressive decline in cognitive function. AD is the main cause of dementia worldwide. Over recent years researchers have strived to find biomarkers to diagnose AD, particularly in the early stages of...
Structural effects of migraine on the retina
1 June 2015
| Claire Howard
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EYE - Neuro-ophthalmology
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Migraine, retinal nerve fibre layer thickness, spectral-domain optical coherence tomography
Migraine is a common, chronic, multifactorial neuro-vascular disorder typically characterised by recurrent attacks of disabling headache and autonomic nervous system dysfunction (migraine without aura). Up to one third of patients also have neurological aura symptoms (migraine with aura). The objective...
Short-term effects of intravitreal bevacizumab on the cornea
1 December 2014
| Khadijah Basheer
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EYE - Cornea, EYE - General
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anterior chamber depth, bevacizumab, central corneal thickness, intraocular pressure, iridocorneal angle, simulated keratometry
Bevacizumab has been extensively used to treat macula oedema and neovascularisation of the retina and it has also been useful in the management of corneal neovascular diseases. This prospective study aimed to provide more information on the effect bevacizumab may...
