Comprehensive review of inherited retinal diseases
3 June 2024
| Zhihang Cheng
|
EYE - Vitreo-Retinal
The authors offer an up-to-date review of inherited retinal diseases (IRDs). In each section the authors discuss the molecular basis of disease, genotype and clinical manifestation. They also discuss the investigation findings and current evidence in the treatment of the...
Contrast sensitivity in myopic eyes
3 June 2024
| Kurt Spiteri Cornish
|
EYE - Vitreo-Retinal
A classification system has been proposed for myopic maculopathy: grade 0 (no myopic retinal lesions), grade 1 (tessellated fundus), grade 2 (diffuse chorioretinal atrophy (CRA)), grade 3 (patchy CRA), and grade 4 (macular atrophy). Tessellated fundus is defined as the...
Persistent subretinal fluid (PSFF) in pneumatic retinopexy (PNR) versus pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD): posthoc analysis of the PIVOT randomised trial
10 May 2024
| Jonathan Chan
|
EYE - Vitreo-Retinal
This is a posthoc study of the PIVOT randomised trial over a 12 month period, to evaluate the functional outcomes of the incidence of PSF in PnR versus PPV following RRD surgery. One hundred and fifty-eight patients were recruited and...
OCTA in diabetic macular oedema treated with intravitreal aflibercept (DOCTA Study)
3 April 2024
| Sofia Rokerya
|
EYE - Vitreo-Retinal
Central vision loss due to diabetic macular oedema (DME) can be attributed not only to presence of the macular oedema itself but also, in some cases, to alterations of the foveal avascular zone (FAZ). The DOCTA trial was a longitudinal,...
All you need to know about PIC
3 April 2024
| Zhihang Cheng
|
EYE - Vitreo-Retinal
This is a review article of punctate inner chorioretinopathy (PIC). The authors detail the epidemiology and clinic presentation of the disease. They recognise the challenge of an accurate diagnosis due to its resemblance to other posterior uveitic entities. Multimodal imaging...
The compendium to clinical evidence in DMO treatment
3 April 2024
| Zhihang Cheng
|
EYE - Vitreo-Retinal
This review article summarises the current evidence base in the treatment options for diabetic macular oedema (DMO). The authors have included many real-world data studies that provided valuable insights into the optimal management of DMO. The authors argue that these...
Macular pigment in relatives of AMD patients
3 April 2024
| Kurt Spiteri Cornish
|
EYE - Vitreo-Retinal
Blue light causes photo-oxidative retinal injury and macular pigment (MP), with lutein, zeaxanthin and mesozeaxanthin as the main components, as a filter that protects the macula from this damage. Previous studies indicated that low levels of macular pigment optical density...
The potential of artificial intelligence and digital health in global eye health
3 April 2024
| Eliott Taylor
|
EYE - Vitreo-Retinal
This article provides an overview of the current landscape of artificial intelligence (AI) and digital health in global eye health. Tan, et al. note that though significant progress has been made in global eye health over the last few decades,...
Genetics counsellors in inherited retinal disease clinics
3 April 2024
| Ian Reekie
|
EYE - Vitreo-Retinal
This is a questionnaire-based study from the USA of genetics counsellors with a primary role working within ophthalmology services. The purpose was to investigate the roles currently undertaken, to assess workload, and to acquire data on the experience of genetics...
Progression of macular atrophy in Stargardt disease
3 April 2024
| Ian Reekie
|
EYE - Vitreo-Retinal
The authors present a study of a cohort of patients with genetically proven ABCA4 gene mutation related Stargardt disease. They aimed to quantify the effect of lesion location and topography on disease progression using fundus autofluorescence imaging. One hundred and...
Intravitreal Bevacizumab for the prevention of postoperative proliferative vitreoretinopathy in high-risk patients
3 April 2024
| Sofia Rokerya
|
EYE - Vitreo-Retinal
This single- centre observational retrospective study was conducted to evaluate the effect of intravitreal injection of bevacizumab at the time surgery for rhegmatogenous retinal detachment (RRD) repair on postoperative proliferative vitreoretinopathy (PVR) in patients at high risk selected by laser...
Clinical predictors of proliferative sickle cell retinopathy
29 March 2024
| Kurt Spiteri Cornish
|
EYE - Vitreo-Retinal
Sickle Cell Disease (SCD) is an inherited disorder resulting in production of Haemoglobin S (HbS), which aggregates in conditions of hypoxia, acidosis or hyperosmolarity. This leads to vascular stasis, thrombosis and ischaemia. The authors present a cross-sectional study (45 consecutive...
