Journal Reviews
Verteporfin shortage: treatment options and outcomes in chronic non-resolving central serous chorioretinopathy
Half-dose photodynamic therapy (HD-PDT) with verteporfin has been the therapy of choice in non-resolving central serous chorioretinopathy lasting longer than four months. Since 2021, a worldwide shortage of verteporfin due to manufacturing issues prompted adjustments in treatment practices. This retrospective,...
Google searches predict pathology after a solar eclipse
This light-hearted review identified that the Google search term, ‘my eyes hurt’ was trending on 8 April 2024, coinciding with the exact time when a total solar eclipse passed over the US. They identified the subregions that searched this term...
Efficacy and safety of intravitreal faricimab in nAMD, DME and RVO
This paper is an analysis of data extracted from 13 eligible studies in the context of neovascular age-related macular degeneration (nAMD), diabetic macular edema (DME), and retinal vein occlusion (RVO), collected from systematic literature search of MEDLINE, Embase, and Cochrane...
Impact of solar eclipses on vision
Solar retinopathy occurs as a result of mechanical and photochemical damage to the retina caused by exposure to excessive light. The authors presented the optical coherence tomography (OCT) and OCT-angiography findings of five patients who looked at the solar eclipse...
Chandelier-assisted versus standard scleral buckling for rhegmatogenous retinal detachment repair. Systematic review and meta-analysis
Despite a significant global decline in standard scleral buckling (SSB) procedures for rhegmatogenous retinal detachment (RRD), it continues to hold its place as an essential treatment option, offering distinct advantages such as cost-effectiveness, preservation of the vitreous, improved final visual...
PAX6 methylation and myopia
The authors present a case control study of 41 adolescents (age 12–14) with myopia and 39 age- and sex-matched non-myopic controls. The myopic patients were sub-divided into mild, moderate and severe myopia subgroups. DNA was extracted from peripheral blood samples...
Update: Non-infectious retinal vasculitis
This review article summarises the update on non-infectious retinal vasculitis (RV). It is primarily classified based on the type of retinal vessels involved and further sub-classified as occlusive or nonocclusive. Clinically it can occur as an isolated ocular entity or...
ILM peeling techniques in myopic traction maculopathy
Myopic traction maculopathy (MTM) is a sight-threatening complication of high myopia including macular retinoschisis (MRS) or foveoschisis, foveal detachment (FD) and myopic macular hole (MMH). Standard surgical treatment is vitrectomy with internal limiting membrane (ILM) peeling, but full-thickness macular hole...
Submacular haemorrhage associated with nAMD: A meta-analysis and meta-regression on use of tPA and anti-VEGFs
The aim of this study was to evaluate the efficacy of a combination of tPA and anti-VEGF in the treatment of submacular haemorrhage (SMH) associated with neovascular age-related macular degeneration (nAMD). A systematic review meta-analysis following PRISMA guidelines, focusing on...
Displacement of submacular haemorrhage – comparative study pneumatic displacement versus subretinal cocktail injection
The authors report a multicentre retrospective interventional case series study comparing the outcome of submacular haemorrhage (SMH) using pneumatic displacement with intravitreal expansile gas versus treatment with pars plana vitrectomy (PPV) versus subretinal injection of tissue plasminogen activator (tPA), anti-vascular...
Type 3 macular neovascularisation (MNV) due to age-related macular degeneration
This paper systematically reviews and summarises the current knowledge on type 3 neovascularisation due to age-related macular degeneration which is defined as neovascularisation originating from the retinal deep capillary plexus that grows towards the outer retina often penetrating the level...
Impact of initial management on relapse in Vogt–Koyanagi–Harada syndrome
In this retrospective, multi-centre, observational study, the impact of the initial management of Vogt-Koyanagi-Harada syndrome (VKHS) was assessed by reviewing the records of all patients diagnosed with VKHS between January 2001 and December 2020 in two French tertiary centres, with...
