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Journal Reviews

OCT angiography in PAMM secondary to CRVO

1 June 2017 | Sofia Rokerya | EYE - Vitreo-Retinal

Paracentral acute middle maculopathy (PAMM) is a recently described manifestation presenting with hyperreflective bands within mid retina on spectral domain optical coherence tomography (SD OCT). The current view is that these findings are markers of ischaemia of deep retinal circulation....

Finasteride and central serous chorioretinopathy

1 June 2017 | Sofia Rokerya | EYE - Vitreo-Retinal

The pathophysiology of central serous chorioretinopathy (CSC) is complex and has not been fully elucidated. Suggested theories include hyperpermeability and increased hydrostatic pressure in the choroidal vasculature, which creates RPE detachments overwhelming the RPE barrier function, leading to accumulation of...

HLA-B27 anterior uveitis

1 June 2017 | Saruban Pasu | EYE - Vitreo-Retinal

HLA-B27 has previously been shown to have an association with uveitis, ankylosing spondylitis, reactive arthritis, ulcerative colitis and psoriasis. The authors of this review provide an update of the epidemiology of HLA-B27 associated ocular disorders. There is great variation amongst...

How many injections in nAMD: ranibizumab vs. aflibercept

1 April 2017 | Eulee Seow | EYE - Vitreo-Retinal

Intravitreal anti-VEGF injections make up a large proportion of the workload in ophthalmology clinics. Since the introduction of aflibercept with eight weekly injections there has been an option to use a treatment which may require less treatment, with potential cost...

Vitrectomy after ocriplasmin for VVMT adhesion of MH study

1 April 2017 | Jonathan Chan | EYE - Vitreo-Retinal

This is a multicentre retrospective study of 51 eyes that received intravitreal ocriplasmin between January 2013 to January 2014 for symptomatic vitreomacular (VMT) +/- macular hole (MH), and then went on to PPV for persistent pathology, comparing a control group...

Treat and extend for PCV

1 April 2017 | Saruban Pasu | EYE - Vitreo-Retinal

This South Korean study investigated the efficacy of a treat and extend regimen (TER) using ranibizumab to treat polypoidal choroidal vasculopathy (PCV). Twenty-nine eyes were included in this retrospective case note review. Of these, five eyes had been treated with...

Preoperative RPE alterations in macular holes

1 April 2017 | Saruban Pasu | EYE - Vitreo-Retinal

This retrospective interventional case series from Japan assessed whether preoperative alterations of the retinal pigment epithelial (RPE) in idiopathic macular holes correlated with postoperative functional and morphological changes in the macula. Fifty-nine eyes had preoperative Spectralis OCT using the ‘detailed’...

An alternative to povidone-iodine for intravitreal injections?

1 February 2017 | Eulee Seow | EYE - Vitreo-Retinal

While povidone-iodine (5% aqueous) preparations have historically been considered the most effective antimicrobial prophylaxis for ophthalmic procedures and have been adopted as routine for intravitreal injections, post-procedure pain is a commonly recognized adverse event of IVI and has typically been...

Licence to save: a UK survey of anti-VEGF use for the eye

1 February 2017 | Sofia Rokerya | EYE - Vitreo-Retinal

This comment article highlights the controversy that exists in the choice for anti-VEGF drugs used for treatment of macular oedema and wet age-related macular degeneration (AMD). Two existing licensed drugs for macular oedema are ranibizumab (Lucentis) and aflibercept (Eylea). A...

RPE tears after intravitreal Lucentis

1 February 2017 | Saruban Pasu | EYE - Vitreo-Retinal

The current hypothesis regarding retinal pigment epithelium (RPE) tears is the contraction and fibrosis in choroidal neovascularisation (CNV) tissue after anti-VEGF therapy can induce rips in the overlying RPE. This South Korean study aimed to identify the association between RPE...

Intravitreal dexamethasone implant for recurrent CMO secondary to IGS

1 February 2017 | Sofia Rokerya | EYE - Vitreo-Retinal

In this prospective study the authors present the data obtained on the efficacy and safety of the dexamethasone implant (0.7 mg) in the treatment of recurrent cystoid macular oedema (PCME) due to Irvine–Gass syndrome in patients with uncomplicated pseudophakia (off-label...

Occurrence and risk factors for RD after PPV in acute postcataract bacterial endophthalmitis

1 February 2017 | Jonathan Chan | EYE - Vitreo-Retinal

This is a prospective multicentre study from France between March 2004 to December 2011 in four university hospitals; 123 consecutive patients treated with pars planar vitrectomy (PPV) were included in this cohort. The rate of retinal detachment (RD) of post-PPV...

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    Fiona Rowe (Prof)

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