Experiences of patients and their families and the impact of Leber hereditary optic neuropathy
3 April 2023
| Lauren R Hepworth
|
EYE - Neuro-ophthalmology
The authors present a qualitative study which aimed to explore the impact of Leber hereditary optic neuropathy (LHON) from diagnosis to present day on both patients and their families. Individuals with LHON and their families were purposively sampled from four...
Did the COVID-19 pandemic affect quality of life of patients newly diagnosed with intra-cranial hypertension?
3 April 2023
| Claire Howard
|
EYE - Neuro-ophthalmology, EYE - General
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COVID-19, Idiopathic intracranial hypertension, pandemic, quality of life
Coronavirus disease 2019 (COVID-19) was identified as a global pandemic by the World Health Organization in March 2020. This article aimed to explore how the care of patients with idiopathic intra-cranial hypertension (IIH) was affected during the COVID-19 lockdown. The...
Using a driving simulator to explore the effect of visual field loss from optic disc drusen
3 April 2023
| Claire Howard
|
EYE - Neuro-ophthalmology
|
Traffic medicine, driving licence, legislation, optic disc drusen, visual field loss
The purpose of this study was to compare driving simulator performance of participants with visual field loss (VFL) from optic disc drusen (ODD) with a normally sighted control group and a group of individuals with glaucoma. Data on performance and...
Can coenzyme Q10 have a protective role in ethambutol-induced retinal ganglion cell toxicity
3 April 2023
| Claire Howard
|
EYE - Neuro-ophthalmology
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Ethambutol, coenzyme Q10, ethambutol toxic optic neuropathy, retinal ganglion cells, tuberculosis
Tuberculosis (TB) is one of the most prevalent infectious diseases, especially in developing or low- income countries. Ethambutol is a widely used drug to treat TB. Ethambutol can cause visual disturbance including ethambutol toxic optic neuropathy (ETON). ETON is one...
Sub-clinical detection methods in multiple sclerosis
3 April 2023
| Claire Howard
|
EYE - Neuro-ophthalmology
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Subclinical multiple sclerosis, axonal degeneration, frequency-doubling perimetry, optic neuritis, optical coherence tomography, standard automated perimetry
Visually symptomatic multiple sclerosis (MS) provides only part of the required information to assist in understanding the disease. Recently, researchers have concentrated their efforts on diagnosing MS cases in the subclinical period. The aim of this paper was to assess...
Case report review of children with septo-optic dysplasia and optic nerve hypoplasia
3 April 2023
| Claire Howard
|
EYE - Neuro-ophthalmology
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Vision, nystagmus, optic nerve hypoplasia, paediatrics, septo-optic dysplasia, strabismus
Septo-optic dysplasia (SOD) and optic nerve hypoplasia (ONH) cause congenital visual impairment. Their aetiology is mostly unknown. The authors aim was to investigate the prevalence of specified ophthalmological features in patients with these disorders. These features included impaired visual acuity,...
Natural history of idiopathic intracranial hypertension depending on incidental or symptomatic presentation
3 February 2023
| Lauren R Hepworth
|
EYE - Neuro-ophthalmology
The authors present a large retrospective review cohort of consecutive patients diagnosed or presumed idiopathic intracranial hypertension (IIH) over a three-year period at a single tertiary centre. Patients on medication with a known aetiology for IIH were excluded. The cohort...
Patterns of binocular diplopia in giant cell arteritis (GCA)
3 February 2023
| Claire Howard
|
EYE - Neuro-ophthalmology
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Diplopia, giant cell arteritis, population-based
Giant cell arteritis (GCA) is a granulomatous vasculitis that targets medium and large sized vessels. Binocular diplopia has been reported in a small number of patients with visual manifestations of GCA. It can be caused by ischaemia in any segment...
Prognosis prediction using clinical findings for fourth nerve palsies
3 February 2023
| Lauren R Hepworth
|
EYE - Neuro-ophthalmology
The authors present a retrospective review of a cohort of patients diagnosed with fourth cranial nerve palsy with more than six months follow-up, over a 10-year period at a single centre. Thirty-five patients were included in the study, and spilt...
Amyotrophic lateral sclerosis (ALS): what happens to eye movements?
3 February 2023
| Claire Howard
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EYE - Neuro-ophthalmology
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Eye movement, amyotrophic lateral sclerosis, anti-saccades; biomarker, pursuit, saccades
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder of upper motor neurons of the corticospinal tract and lower motor neurons in brainstem nuclei and the anterior horn of the spinal cord. Limited literature is available on abnormal ocular movements in...
Retrospective review of visual outcomes in Idiopathic intracranial hypertension (IIH)
1 December 2022
| Claire Howard
|
EYE - Neuro-ophthalmology
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Idiopathic intracranial hypertension, Pseudotumor cerebri, visual outcome
Idiopathic intracranial hypertension (IIH) is a clinical syndrome characterised by headache and papilloedema that can lead to significant visual morbidity. IIH is diagnosed by the modified Dandy criteria, which include normal neuroimaging and cerebrospinal fluid (CSF) composition, high CSF opening...
Does religious fasting affect intraocular pressure or retinal parameters?
1 December 2022
| Claire Howard
|
EYE - Neuro-ophthalmology
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Religious fasting, Retina, macula, optical coherence tomography angiography
Nearly one billion Muslims fast every year during the month of Ramadan. Due to the difference between the lunar and solar calendars, religious fasting time can range from 11 to 17 hours per day. This prolonged abstinence from food and...
