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Genetic analysis of choroideremia families

1 February 2016 | | Retina / Uvea / Vitreous | CHM, REP1, choroideremia, rab escort protein 1
Choroideremia (CHM) is a rare X linked recessive chorioretinal dystrophy. Symptoms include nyctalopia and progressive peripheral field loss. Female carriers may have mild symptoms. Choroideremia is known to be caused by a mutation in the CHM gene. A multicentre human...
Neuro-Ophthalmology journal cover image

Rare presentation of giant cell arteritis in Chinese subjects

1 September 2023 | | Neuro-Ophthalmology | non-arteritic anterior ischaemic optic neuropathy, Chinese, central retinal artery occlusion, Giant cell arteritis, ocular ischaemic syndrome, posterior ischaemic optic neuropathy
Only a few case reports of biopsy-proven GCA (BpGCA)-associated vision loss in Chinese subjects have been published. This paper presents three elderly Chinese subjects with BpGCA who presented with vision loss. A search of the literature was also conducted to...

A new observation point: updating the nomenclature and classification with OCT

3 June 2021 | | Ophthalmology, Optometry, Imaging, Retina / Uvea / Vitreous
The evolution of ophthalmic imaging technologies has been particularly rapid over the last few years. The author provides an update of the current terms for common signs and pathologies observed using optical coherence tomography. My experience as an ophthalmic technician,...

Correlation between anti-retinal antibodies and proliferative vitreoretinopathy (PVR)

1 October 2018 | | Retina / Uvea / Vitreous | Proliferative vitreoretinopathy, aqueous humor, autoantibodies, retinal detachment, vitreous
The pathological basis of PVR is not clearly understood and there are no effective medications targeting this condition. This cross-sectional study looked at the possible association of anti-retinal antibodies with patients with PVR and retinal detachment (RD). Aqueous and vitreous...

The effect of everolimus on retinal pigment epithelium and proliferative vitreo-retinopathy

1 August 2018 | | Retina / Uvea / Vitreous | Everolimus, mammalian target of rapamycin (mTOR), proliferative vitreoretinopathy, retinal detachment, ribosomal protein S6 (RPS6)
The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...

Money never sleeps

5 April 2022 | | Ophthalmology, Retina / Uvea / Vitreous
“I want you to deal with your problems by becoming rich” As declared by Jordan Belfort in a motivational speech to his staff in the film Wolf of Wall Street (2013). Unfortunately, medicine as a career does not lead to...

My top five Apps for UK-based general ophthalmologists

1 October 2021 | | Ophthalmology, Optometry
The way we interact in society is changing as more of us are becoming ‘digital natives’: individuals who are in close contact to the internet and expect to integrate smart devices with our daily lives. This was stereotypically a term...

Twenty-five years in retina

1 February 2019 | | Ophthalmology, Retina / Uvea / Vitreous
In the next of our articles celebrating 25 years of Eye News, the authors look at how the retina specialty has changed over this time and ask what the future might hold. Retinal disease management has benefited from great advances...

A focus on Pakistan’s growing eye care needs: over 43 million patients treated for curable blindness free of charge

5 February 2020 | | Ophthalmology
With 90% of the world’s visually impaired living in developing countries, Pakistan is no exception to this on-going global healthcare challenge. Despite massive leaps over the last few decades in targeting this issue, the World Health Organisation (WHO) reports that...

A near miss

1 February 2019 | | Ophthalmology, Retina / Uvea / Vitreous
A 55-year-old gentleman presented with a ‘blurry patch’ to his left eye which he had noticed for the past two months. The visual acuity with correction was 6/5 in the right eye and 6/6 in the left eye on the...

The management of antiplatelets and anticoagulation in elective ophthalmic surgery

1 April 2016 | | Orbit, Oculoplastics
Clinical scenario: A 57-year-old gentleman who is scheduled to have Mohs micrographic surgery and reconstruction for a medial canthal basel cell carcinoma (BCC) has been started on aspirin and clopidogrel following a coronary stent three weeks ago. Does the antiplatelet...

Traumatic injuries from foam Nerf bullets

5 June 2023 | | Emergency Ophthalmology, Paediatric Ophthalmology / Strabismus
Background Three patients are presented in this case report: an adult and two children which were subjected to ocular injuries from Nerf gun bullets. Generally, Nerf guns are considered safer than airsoft guns. While there are many papers on airsoft...