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Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants

“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...

Surgical outcome reporting for exotropic DRS

The authors report the surgical outcomes of patients with exotropic Duane’s retraction syndrome (DRS) in a retrospective study of 73 patients; 67 unilateral cases. Patients had a mean age at surgery of 14.11 years (range 2-33). The left eye was...

What’s new in glaucoma? Clinical trials drive practice changes, surgical advancements gather pace

Rod McNeil reviews the latest developments in the treatment of glaucoma in the UK. Primary open-angle glaucoma (POAG), which accounts for over two-thirds of all glaucoma cases, has an estimated UK prevalence in 2017 of approximately 2% of people over...

SLT versus medication for OAG

This paper appraised existing randomised clinical trials (RCTs), which compared selective laser tabeculoplasty (SLT) with medical therapy for open-angle glaucoma (OAG), and performed a systematic review and meta-analysis. A total of 1229 patients in eight trials were included from PubMed,...

Diplopia after cataract surgery – risk factors

The risk factors for binocular diplopia after uncomplicated cataract surgery in adults were studied to analyse the patterns of ocular motility and clinical causes. This was a retrospective review of 40 patients; 25 female. Onset of diplopia was at a...

Bimedial resection surgery dose-response

The purpose of this study was to evaluate the dose-response relationship for primary bilateral medial rectus (MR) resection in 49 children with exotropia. Fifty-seven percent of children were male and mean age at surgery was 6.7 ±5.3 years. Mean preoperative...

Large series profiling skew deviation

A retrospective notes review was completed for patients identified as having skew deviation. The authors outline their exact definition of skew deviation within the methods of the paper. One hundred and fifty-seven patients were identified, it is not clear over...

Surgery for acquired distance esotropia

The purpose of this study was to evaluate the outcome of this surgical approach in the treatment of divergence insufficiency esotropia. This was a retrospective review of 18 patients aged on average 49.6 years; 77% were female. Preoperatively the distance...

Conservative management of concomitant strabismus

The aim of management for all patients with strabismus should centre around four goals: to prevent amblyopia, to alleviate symptoms, to restore binocular single vision (BSV) and to improve ocular alignment. The conservative management options available for strabismus include observation,...

Ocular motility disturbances after glaucoma drainage device

This is a cross-sectional study of children (<17-years-old) with a glaucoma drainage device (GDD) (Ahmed vs Baerveldt) implanted consecutively by a single surgeon from the Toronto group, between September 2006 and May 2018 and who had an ocular motility examination...

Choroidal melanoma – breaking bad news

Case report A 55-year-old Caucasian female presented to her general practitioner with a three-month history of headaches and worsening blurred vision in the left eye. On further close questioning, she reported no eye pain, intermittent floaters and flashes of light...

Surgical outcomes for constant and intermittent exotropia

This study evaluated the surgical results for constant and intermittent exotropia to investigate the factors that might influence the surgical results in a Scandinavian population. This was a retrospective study from 2011-2015 during which time 633 patients had strabismus surgery...