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Intravenous paracetamol in orbital surgery

This is a large prospective study of the effect of intravenous acetaminophen (paracetamol) in orbital surgery. The study included three groups of 50 patients. One group had no i.v. paracetamol, the second 1g of i.v. paracetamol within 30 minutes of...

Intravenous ketorolac during DCR

This study compares pain scores postoperatively between patients that received intravenous ketorolac (IVK) pre, intra or immediately postoperatively and a control group that did not receive it. The authors state that the patients were randomised, however it is not described...

Effect of intravenous mannitol in post vitrectomised eyes

The purpose of the study was to evaluate the effect of intravenous mannitol 20% on intraocular pressure in vitrectomised silicone-oil filled eyes. A prospective analysis of consecutive patients was undertaken with their fellow eyes taken as controls. Thirty-one patients were...

Primary intravenous chemotherapy (IVC) for Group D retinoblastoma

A retrospective review is reported of 64 group D retinoblastoma (RB) eyes (52 patients) treated with primary IVC, between 2002 and 2014 from two centres, in the UK and US. The median age at presentation was 11 months, 35 (67%)...

Correlation between peak intraocular pressure following water drinking test and pulsed methylprednisolone therapy

Steroids have long been known to cause increased intraocular pressures (IOP) in susceptible patients. Intravenous methylprednisolone is used to treat many rheumatological conditions and one of the risks is raised intraocular pressure. It would be useful to find patients at...

Cavernous sinus thrombosis and orbital cellulitis

This is a report of six cases of combined orbital cellulitis and infective cavernous sinus thrombosis, with a literature review. The average age was 39 years, four were male and two were intravenous drug users. All had sinusitis, usually involving...

VKH outcomes with pulse IV steroids

This is a retrospective review of clinical case notes records of 111 Vogt-Koyanagi-Harada (VKH) patients between 1999 and 2015 from a single centre in Tokyo, Japan. The mean age at presentation was 41 years and the median follow-up period was...

IAC vs. IVC chemotherapy for RB

This a single centre retrospective review of consecutive patients between 1997 and 2014, of all sporadic unilateral retinoblastoma (RB) group D cases, treated with combined intravenous chemotherapy (IVC) and focal treatments (1997- 2008), or intra-arterial chemotherapy (IAC) treatment (2008 to...

Pain score assessment in babies undergoing treatment for ROP

The aim of this study was to assess neonatal pain scores during laser treatment for retinopathy of prematurity (ROP) under sub-tenon anaesthetic with oral or rectal sedation. Sixty-two babies were included who have had ROP laser treatment over a seven...

An unusual presentation of dysthyroid orbitopathy

The authors present a case of a 50-year-old male smoker who presented with bilateral gaze evoked amaurosis (GEA), i.e. the patient was aware of loss of vision in all gaze positions other than the primary position. The patient was being...

Bisphosphonates can cause orbital inflammation

The authors describe four patients with bisphosphonate induced orbital inflammation and review a further 25 cases in the literature. Intravenous zoledronate was the most common precipitant (76% of cases) with the mean time until onset of inflammation being three days...