You searched for "inflammation"
A novel way to distinguish between types of anterior ischaemic optic neuropathy
The authors evaluate the monocyte to high-density lipoprotein (HDL) ratio (MHR) in patients with arteritic and non arteritic anterior ischaemic optic neuropathy (A-AION / NA-AION). A distinction between the two types of AION is essential to begin appropriate treatment, which...
Profile of sympathetic ophthalmia (SO)
The authors undertook this study to examine the clinical profile of patients aged <18 years with SO over the past 20 years. This was a hospital-based retrospective study from 1997 to 2017. SO is a diagnosis of bilateral panuveitis following...
Migraine and risk of retinal artery occlusion
This retrospective cohort study assessed whether migraine was associated with an increased risk of retinal artery occlusion. They reviewed a large insurance database of 418,965 patients who suffered with migraines between 2007 and 2016. These were then matched with an...
Prevalence and incidence of uveitis
Uveitis encompasses a group of diseases characterised by the inflammation of fovea uvea which are potentially vision threatening. However, the frequency of this condition is unclear. This systematic review and meta-analysis aimed to provide estimates of the frequency of uveitis...
Evaluation of fluocinolone acetonide in the management of BRC
This is a single-centre, retrospective, intervention study of 15 eyes of birdshot retinochoroiditis (BRC) patients who received Iluvein, with a mean follow-up period of 31 months. Five eyes had previously received dexamethasone intravitreal implant 0.7mg (Ozurdex). Fluorescein angiography (FA) showed...
Presenting and diagnostic signs of retinoblastoma
This study revisits the presenting signs of retinoblastoma (RB) in the context of current best practice with respect to diagnosis and assessment of RB. This was a retrospective review of 131 consecutive cases, excluding those with positive family history over...
Diagnostic and prognostic roles of serum interleukin-6 in patients with uveitis
This is a retrospective observational case series investigating the diagnostic and prognostic role of serum interleukin (IL)-6 in patients with uveitis involving 80 patients – 60 patients (75%) with normal IL-6 levels and 20 patients (25%) with high IL-6 levels....
Clinical features of ocular syphilis
The study looked at 24 patients (20 males, four females) with serological evidence of syphilitic infection who presented to a tertiary ophthalmic centre. Ocular involvement was the first manifestation of syphilitic disease in 96% and Human Immunodeficiency Virus (HIV) seropositivity...
A novel presentation of optic disc oedema with syphilis
Optic disc oedema (ODE) due to syphilis without visual compromise has been primarily attributed to papilloedema from raised intracranial pressure or optic perineuritis from optic nerve sheath inflammation. These terms were proposed before magnetic resonance imaging (MRI) was largely available....
IgG4-related disease or Graves orbitopathy
This is retrospective review of patients who had been diagnosed with both IgG4-related ophthalmic disease (IgG4-ROD) and Graves orbitopathy over a four year period. Eight patients were identified. The diagnosis of IgG4-ROD was based on 10 or more IgG4+ plasma...
Use of amniotic membrane in second stage Hughes tarsocunjunctival reconstruction
This is a retrospective, non-comparative interventional case series of 30 patients who underwent amniotic membrane transplantation to lower lid margin as part of Hughes lid reconstruction to prevent a hyperaemic, hypertrophic conjunctival margin with excessive discharge. Patients undergoing more than...
