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Immunoglobulin G4-related ophthalmic disease – what is it? (Part 1)

Part 1: Epidemiology, classification, radiology, histopathology and associations (see Part 2 here) In this two-part series, Li Yen Goh reviews IgG4 disease and reminds us of diagnostic challenges faced. Introduction Immunoglobulin G4 (IgG4) disease is a recently recognised idiopathic systemic...

The bionic eye – behind the headlines

Multiple visual prosthetic projects and other vision regeneration initiatives being tested in preclinical and clinical development worldwide illustrate continuing progress and opportunities in addressing profound blindness from hereditary retinal diseases and other causes (Table 1). Three implantable bionic vision systems...

Clinical and management strategies in glaucoma practice: perspectives from international glaucoma specialists

Management options and outcomes in glaucoma practice were reviewed at the 7th Moorfields International Glaucoma Symposium, held in London on 24 January 2015. This article summarises perspectives from international glaucoma specialists on debated issues in topical therapy, glaucoma surgery, diagnostic...

Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants

“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...

Guide to Gaining Approval for a Clinical Study

This article focuses on gaining approval for clinical research involving NHS patients, although the principles can be applied to other types of research. The intention is to give an overview of the requirements for setting up a research study, but...

Blinded by an Ofsted inspection

Introduction The Association of Health Professions in Ophthalmology (AHPO) is a charity, whose objectives are to promote the practice, education, training and research in ophthalmology and vision science in the UK. The extraordinary developments in diagnostic equipment and technologies have...

The results of the last survey Oct22

I thank everyone for their time in responding to this edition’s survey questions. The first question relates to an issue I have previously discussed around consent for second eye cataract surgery. I touch on this point again for two reasons....

How to nearly (but not quite) get into ST1 ophthalmology training – some reflections

Ophthalmology is often considered to be an elite, highly competitive specialty, with little room for failure. Candidates and trainees tend to cultivate a certain urbane and confident style, and the bottleneck at ST1 can feel rather intense. The majority of...

Eye testing at home – developing an app for measuring vision

COVID-19 has made home vision monitoring a necessity. Stephanie Campbell shares how her idea for a vision testing app that would engage patients became a reality. Months before COVID-19 first began to mutate to its human host, there was a...

Paediatric spectacle dispensing: more than a frame and lenses

It’s incredibly rewarding to fit a child’s first pair of spectacles and see their face light up; looking around to see the wider world for the first time. Sometimes it is so obvious that even the most reluctant parent will...

A complicated case of cytomegalovirus viremia: “What would you do doctor?”

Mrs W walked gracefully into my urgent care clinic. It was another busy session and I hoped she did not have anything serious going on which might slow the clinic further. She was an elegant 72-year-old lady who seemed like...

A closed angle seldom comes alone

Case report An 89-year-old lady with dementia was referred to me out of hours by her GP with a few days history of an angry looking left eye for suspected elevated intraocular pressure (IOP). I discovered that this lady first...