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Detecting apoptosis in retinal cells

This is a review paper in which the authors summarise the transitioning of techniques detecting apoptosis from bench to bedside, along with the future possibilities they encase. Detection of Apoptosis in Retinal Cells (DARC) technology can be used as a...

RaScaL Study

The RaScaL study was a six month, single-centre, controlled, prospective phase I/II study in which subjects with diabetic macular oedema (DME) and associated peripheral nonperfusion on ultrawide-field fluorescein angiography (UWFA) were randomised to: (1) study arm: ranibizumab (0.5 mg) injection...

Dacryocystosclerotherapy as an alternative to dacryocystectomy

In this article, the authors evaluate the role of sclerosing agents in dacryocystosclerotherapy (DCST) and aim to see whether it is an alternative to dacryocystectomy (DCT) in a specific group of patients. Thirteen lacrimal drainage systems of 10 patients with...

Atlas of Wide-Field Retinal Angiography and Imaging

Through extensive illustrations, this book, comprehensively yet concisely, covers the diagnostic speciality of wide-field retinal angiography and imaging. There are 15 chapters with contributions from 29 leading experts in this particular field who are mainly based in the USA, but...

Assessment and management of dry eye disease

This paper is an update on the assessment and management of dry eye disease (DED). According to the second International Dry Eye Workshop 2017, “Dry eye is a multifactorial disease of the ocular surface characterised by a loss of homoeostasis...

Rebamipide 2% for dry eye

Rebamipide is a quinolinone derivative that has been found to increase mucin production and the number of conjunctival goblet cells. A previous phase two study has shown rebamipide 2% to be better than placebo in improving the ocular surface and...

Multimodal Retinal Imaging

Understanding of rapidly advancing retinal imaging techniques is important as they have changed the management of retinal conditions considerably. Interpretation of these tests is a vital skill in the armamentarium of every practising ophthalmologist. The book is directed at general...

OCT changes in chronic optic neuropathy

The authors evaluated optical coherence tomography (OCT) angiography in 10 patients who suffered various types of chronic optic neuropathies. Glaucoma is known to cause a decrease in peripapillary perfused capillary density on OCT angiography. However, other optic neuropathies have not...

Conjunctivochalasis and aqueous tear deficiency – which one causes symptoms?

This review sought to determine whether conjunctivochalasis (CCh) obliterates the fornix tear reservoir and thus mimics aqueous tear deficiency (ATD). Patients were divided into two groups, with aqueous tear deficiency (CCh +ATD) or without (CCh –ATD), based on results of...

Treatment of Sjogren’s Syndrome dry eye in mouse model

Sjogren’s syndrome (SS) is a chronic autoimmune disease characterised by inflammation of the exocrine glands, specifically the salivary and lacrimal glands that produce saliva and tears, respectively. The immune-mediated attack on the salivary and lacrimal glands leads to the development...

Managing orbital compartment syndrome

This experimental study using cadaveric models was done to evaluate the surgical technique effective in relieving orbital compartment syndrome. Twelve cadaveric orbits were injected with blood analogue stained with fluorescein. Pressure probes were inserted in superotemporal (advanced 40mm into orbit)...