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Neurotrophic keratitis

The authors present an overview of the aetiology, diagnosis, current and future management options of neurotrophic keratitis. This is a degenerative corneal disease that occurs following the compromise of trigeminal innervation, leading to hypoesthesia and / or anaesthesia. The aetiology...

Risk factors and untreated POAG

The authors examined 50 untreated open angle glaucoma patients to determine if there was an association between the level of glaucomatous damage and documented risk factors. In this study the authors measured the extent of morphologic and functional glaucomatous damage...

Erythropoietin in healing corneal epithelial defects in rabbits

Corneal epithelial defects heal slowly in patients with diabetes, limbal stem cell deficiency and severe chemical burns. Erythropoietin is a glycoprotein hormone that promotes red blood cell proliferation and inhibits apoptosis of erythroid progenitors as well as nonhematopoietic cells. In...

Cystoid macular oedema following cataract surgery

This review covers the history, incidence, diagnosis, risk factors, pathophysiology and medical management of postoperative macular oedema (PCMO), with a particular emphasis on key contemporary studies and novel observations. The authors revisit the incidence of well-established risk factors including intraoperative...

Colour Doppler imaging before and after orbital decompression in thyroid eye disease

In this prospective, uncontrolled study euthyroid patients with moderate to severe inactive thyroid eye disease underwent colour Doppler imaging before and after orbital decompression. Patients with dysthyroid optic neuropathy, corneal breakdown, systemic disease (diabetes, cerebrovascular accident, cardiovascular and peripheral vascular...

Microbiology, risk factors and outcomes of microbial keratitis in Sydney, Australia

The authors present a retrospective case series including all patients with microbial keratitis and ocular surface diseases (OSD), including dry eye, blepharitis, Stevens-Johnson syndrome and / or ocular cicatricial pemphigoid, over a five-year period between 2012 and 2016. A total...

Is optic disc drusen a risk factor in young patients with anterior ischaemic optic neuropathy?

This retrospective cross-section multicentre study reviewed 65 patients all younger than 50-years-old with non-arteritic anterior optic neuropathy (NA-AION) between April 2017 and March 2019. The purpose of this study was to investigate if there was a link between Optic Disc...

Sjogren’s syndrome in association with ophthalmoplegia

This is a case report of a 28-year-old female complaining of horizontal and vertical diplopia with inability to move her right eye and sudden onset right ptosis. She complained of retro-orbital pain with headache and a foreign body sensation in...

COVID-related mucormycosis

The authors report a retrospective case-control study of 73 patients with COVID-19 associated mucormycosis (CAM) between 1st March and 30th May 2021. They compared various factors between the two groups – patients who survived CAM (47 [64%]) and those that...

Clinical features and mortality of endogenous panophthalmitis in China

This longitudinal cohort study aimed to report the clinical features, treatment strategy, and mortality of 15 consecutive patients (16 eyes) with endogenous panophthalmitis (EP) at a tertiary medical centre of the largest eye centre in Northern China. Mean age was...

Retrobulbar amphotericin B for rhino-orbital-cerebral mucormycosis

Rhino-orbital-cerebral mucormycosis (ROCM) is a rare and often fatal infection usually occurring in immunocompromised patients from diseases such as diabetes, haematological malignancy and solid organ transplantation. Current standards of care include systemic antifungal therapy and debridement, including exenteration. This study...