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FAQs about cerebral visual impairment (CVI): identifying and helping those affected

Cerebral visual impairment is common in both adults and children, yet the diagnosis can easily be missed unless one is tuned into the presenting features. This article provides a succinct introduction to this important topic. What is vision? Vision is...

Serology testing in periocular inflammatory disease

This is a review article of serological tests in thyroid eye disease, IgG4-related disease and myasthenia gravis. The authors provide an overview of the current serology with a brief description of how they relate to the pathogenesis of each condition....

Help the VISION 2020 LINKS & Networks Programme to save children’s sight and lives

The LINKS & Networks Programme was established at the International Centre for Eye Health (ICEH), London School of Health and Tropical Medicine (LSHTM), 20 years ago to improve the quality and quantity of eye health services in low- and middle-income...

You want to do paediatric ophthalmology? Seriously?

Completion of Core Training is approaching fast and you begin to wonder three things. One, where do you want to live? Two, is anyone going to be retiring there soon? Three, what subspecialty do you want to do? In an...

PD-1 and PD-L1 in exenteration specimens

This is an immunohistochemical study looking at variation in the expression of the programmed death-1 receptor (PD-1) and the programmed cell death ligand-1 (PD-L1), comparing cutaneous malignancies which invaded the orbit with uncomplicated nodular basal cell carcinomas. The authors retrospectively...

Differential inhibition of EAU by CTLA4 and IL-6

Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...

A game changer in meibomian gland treatment

Introducing the new Meibomian Gland Dredger by Gaush Meditech Ltd. Meibomian gland dredging is important in the treatment of dry eye and has a great influence on treatment outcomes. Many types of dye eye treatment combined with meibomian gland dredging...

Falkirk girl with sight loss is World Book Day winner

Grace Kidd, 9, from Falkirk, is the winner of a creative writing competition hosted for the first time by leading sight loss charity, RNIB, to mark World Book Day.

In conversation with Robert Henderson

Revolutionary eye treatments offer hope for children facing blindness from CLN2 batten disease. Robert Henderson discusses this, and his use of Heidelberg Engineering’s Spectralis device to better combat it. Pioneering research from Great Ormond Street Hospital (GOSH) and the University...

Periocular sweat gland carcinomas

This is an interesting review of a rare group of tumours which together comprise the adnexal sweat gland carcinomas. Although there are only 22 patients, this is the largest cohort ever published. The authors summarise the clinical presentation, stage, management...

Hospital wins funding to investigate sickle cell sight loss.

The hospital trust is the first in the UK to lead on a research project to understand the impact of sickle cell disease on eyesight.

Cavernous sinus syndrome

Anatomically the cavernous sinus is a plexus of multiple veins that are connected and within this plexus there are several important vascular and neurological structures. These include cranial nerves III, IV, V1 (and sometimes V2), VI as well as the...