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Oxford Rheumatology Library: Sjögren’s Syndrome
This is a handy little book which covers everything you need to do know (and then some) about Sjögren’s syndrome. It is split into nine sections: Epidemiology, genetics and disease burden Diagnosis and clinical assessment Oral features Ocular features Fatigue,...
Silicone hydrogel contact lenses versus autologous serum drops for dry eyes in Sjörgen syndrome
A total of 37 patients with Sjörgen syndrome (SS) related dry eyes reporting symptoms on standard therapy with artificial tears and anti-inflammatory drops were evaluated in this trial. They were randomly assigned to additional treatment with either balafilcon A silicone...
Bilateral internuclear ophthalmoplegia
Bilateral internuclear ophthalmoplegia (INO) has been linked with various pathological conditions of the central nervous system such as multiple sclerosis, stroke, tumours and brainstem inflammatory processes. This unusual case report describes a case of a 45-year-old female patient presenting with...
Sjogren’s syndrome in association with ophthalmoplegia
This is a case report of a 28-year-old female complaining of horizontal and vertical diplopia with inability to move her right eye and sudden onset right ptosis. She complained of retro-orbital pain with headache and a foreign body sensation in...
Treatment of Sjogren’s Syndrome dry eye in mouse model
Sjogren’s syndrome (SS) is a chronic autoimmune disease characterised by inflammation of the exocrine glands, specifically the salivary and lacrimal glands that produce saliva and tears, respectively. The immune-mediated attack on the salivary and lacrimal glands leads to the development...
Ovarian hormones drive onset of Sjogren’s disease in mice
Sjogren’s syndrome (SS) is a debilitating, sight-threatening, systemic autoimmune disease with no effective treatment available. SS is characterised by lacrimal gland lymphocytic infiltration and epithelial cell death, as well as by the presence of serum autoantibodies. Patients have severe dry...
Ocular Surface Disorders
This publication provides an excellent overview of ocular surface disease (OSD). Dry eye disease (DED) is the commonest OSD. There has been a recent explosion, both in terms of its diagnosis and the treatments that are available. A textbook that...Does a gut-eye axis exist?
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Does a gut-eye axis exist? Over a decade ago, the Human Microbiome Project was launched by...Blinking blepharitis has a lot to answer for…
Never ignore the small things’…someone once said. There is no doubt blepharitis is one of the most common eye conditions encountered daily, but with the typical pressures of a busy outpatient department, the management of more obvious, sight-threatening conditions necessarily...
Serology testing in periocular inflammatory disease
This is a review article of serological tests in thyroid eye disease, IgG4-related disease and myasthenia gravis. The authors provide an overview of the current serology with a brief description of how they relate to the pathogenesis of each condition....
