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HtrA1 enhances cell senescence
A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...
Ranibizumab for the treatment of age-related macular degeneration
This multicentre randomised prospective open label study compared 0.5 versus 2mg of ranibizumab in patients with submacular retinal pigment epithelial (RPE) detachment due to age-related macular degeneration. Four treatment regimens were used for the two strengths either monthly for 12...
Comparison of SS-OCT and SD-OCT in polypoidal choroidal vasculopathy
Swept source OCT (SS-OCT) is known to have a longer wavelength than spectral domain OCT (SD-OCT), allowing deeper penetration into retinal and choroidal layers. The aim of this study was to investigate whether SS-OCT is superior to SD-OCT in imaging...Medical and eye health teams defy odds to deliver treatments for trachoma in Ethiopia, but millions worldwide risk return of disease amid UK aid cuts
Ophthalmologists, nurses, and eye health workers in Ethiopia defied the odds to treat millions with trachoma-fighting antibiotics and surgeries - despite cuts to UK Aid assistance threatening eye care. This World Neglected Tropical Diseases Day Orbis, the international eye care...What's trending Jun/Jul 2020
Here in the UK, we’ve been in lockdown since 23 March 2020, with much of the rest of the world entering degrees of lockdown since February-March 2020. COVID-19 has dominated the headlines and social media, so without further ado, I...The 2020 Milgram Experiment
Will ophthalmology recover from COVID-19? Learning Curve columnist Gwyn Samuel Williams shares his thoughts on the developing impact of the pandemic “It’s busy today,” the nurse in green chuckles. “There are six patients I think.” Six. This clinic is designed...Uncertainties and opportunities in ophthalmology training after the COVID-19 pandemic
Alexander Jones asks what impact the current pandemic will have on ophthalmology trainees. In my work as a Clinical Teaching Fellow, I have to admit that chaos is uncommon. Neither the anxious excitement of rushing to help an unwell patient...Effect of the COVID-19 Urgent Eyecare Service on patient referrals to general practitioners and Hospital Eye Service
The COVID-19 Urgent Eyecare Services (CUES) was developed to relieve the demands of hospital ophthalmology, aiming to allow patients to have remote consultations and be managed by community optometric practice. This was because access to Hospital Eye Service (HES) Ophthalmic...Obituary: a heartfelt goodbye to Roger Pope
One of the most admired of UK opticians, Roger Pope, holder of two Royal Warrants, has sadly passed away leaving a legacy as the greatest colleague and friend to the optical community.Decontamination and sterilisation of surgical instruments and medical devices
Ann-Marie Ablett is a Theatre Nurse and Team Leader who volunteers with Orbis. This has allowed her to gain a wealth of experience on ophthalmic procedures, nursing in under-privileged parts of the world, leadership, management and use of scarce resources....Management of diabetic macular oedema in vitrectomised eyes
Diabetic macular oedema (DMO) is one of the leading causes of blindness; its prevalence is on the rise with progressive increase in numbers of people suffering from diabetes. The management of DMO has evolved significantly over the past few years....
