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Oral Ibuprofen reduces early bleb failure in high risk trabeculectomy
In this retrospective cohort study, 288 eyes of 273 patients (mean ±SD age: 68.56 ±10.47 y; 32.60% females) with primary glaucoma who underwent trabeculectomy / phacotrabeculectomy at the Singapore National Eye Centre between April 2020 and April 2021 with a...
Evaluation of the association between diabetes autoantibodies and development of early diabetic retinopathy in type 1 diabetes
This study was conducted to investigate the relationship between diabetes autoantibodies and the development of early diabetic retinopathy (DR) to assess the role of autoimmunity in retinopathy. The study included 18 boys and 44 girls with type 1 diabetes mellitus...Ophthalmology history and examination – a guide for medical students
*First author Students have very little exposure to ophthalmology during their years at medical school. Teaching consists of a handful of lectures followed by a short placement in which students are expected to practise histories and examinations on patients with...Treatment of diabetic macular oedema
Diabetic macular oedema (DMO) is a common complication associated with diabetic retinopathy, and the most common cause of visual impairment in diabetes [1]. With predicted rising levels of diabetes (in England by 2025 the estimated population with diabetes will be...
Complement Factor H and Factor H-Like protein are expressed in human RPE cells
The role of inflammation in age-related macular degeneration (AMD) is well documented and the association of AMD with the inflammatory marker C-reactive protein (CRP) and members of the complement system underline the role of complements in AMD. Human complement factor...
Enzymatic clearance of anterior chamber infiltrate in uveitis
Aqueous humour (AH) which fills the anterior chamber (AC) of the eye provides nutrients to the cornea and the lens. Clearance of cellular and particular matter from AH is necessary for good visual acuity. In part this is achieved by...
HtrA1 enhances cell senescence
A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...COMPlog – Electronic visual lane software
COMPlog is software designed to replace physical Snellen and LogMAR charts. We have been using COMPlog since 2017 in the unit where I work. Some readers may find our experience, and reasons for choosing this product, interesting. This article is...Another plant-based remedy for the eye?
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Another plant-based remedy for the eye? What do the nicknames Mary Jane, tea, and 420 all...The approach to trabeculectomy postoperative complications
Performing a trabeculectomy is like giving birth to a baby. It may be traumatic and there is scope for devastating error but once the operation is completed only then does the real work begin. The bleb must be nurtured into...Understanding and confronting bacterial endophthalmitis
Abdus Samad Ansari highlights the importance of early recognition of this condition using an unusual presentation. Endophthalmitis is a medical emergency with devastating consequences. Despite adequate treatment, severe cases frequently result in permanent blindness. Endophthalmitis involves inflammation of both the...
