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Genetic therapy gives infants life-changing improvements in sight

Four young children have gained life-changing improvements in sight following treatment with a pioneering new genetic medicine through Moorfields Eye Hospital and UCL Institute of Ophthalmology, with the support of MeiraGTx. The children were born with a severe impairment to...

Guide to Gaining Approval for a Clinical Study

This article focuses on gaining approval for clinical research involving NHS patients, although the principles can be applied to other types of research. The intention is to give an overview of the requirements for setting up a research study, but...

Portable vision reading device shows promise for low vision after brain injury

The authors report a small sample cohort study evaluating the impact of a portable vision reading device (OrCam Read) on vision-related quality-of-life and independent functional status in patients with low vision due to stroke or brain tumours. Six patients with...

Useful digital resources for the modern ophthalmologist

In the age of the internet and a smartphone at everyone’s fingertips, here are some free resources I have found to be useful on the job, and hopefully will be of use to you too. Feedly (Android/iOS): Better known as...

Incidence and risk factors of ocular hypertension following PPV and SOI

In this prospective, interventional study the authors evaluated the risk factors for elevated intraocular pressure (IOP) after pars plana vitrectomy (PPV) with silicone oil injection (SOI). This study included 254 eyes of 254 patients, with a mean age of 55.33...

Idiopathic intracranial hypertension (IIH)

IIH is a medical condition where the intracranial pressure (ICP) is raised without an obvious cause. The cerebrospinal fluid (CSF) is produced in by the choroid plexus in the lateral ventricles and the roof of the third and fourth ventricles,...

Baerveldt Glaucoma Implant (BGI)

The authors describe surgical outcomes using the BGI and compared the different techniques used. The main differences described in the implantation technique include the use of a prolene stent in the tube, or fixation of the tube to the sclera....

Less extrusion of StopLoss Jones tubes

This is a retrospective comparison of the survival of StopLoss Jones tubes with conventional Lester Jones tubes. Between 2014 and 2016, 31 StopLoss and 59 Lester Jones tubes were inserted. The authors compared the extrusion and sinking-in rates between the...

BT outcomes under open versus closed sky technique

This retrospective study compared open versus closed sky BT injection techniques without electromyography (EMG) control in 135 patients (31 open sky and 104 closed). Patients were aged 1-50 years for open sky and 2-34 years for closed. There was a...

BT vs primary surgery for infantile esotropia

In this study, the success rate of treatment for infantile esotropia (IET) patients who had surgery because of under correction after botulinum toxin (BT) is compared to those having primary surgery. The study included 52 patients (27 male) with mean...

Strabismus prevalence in a Pakistan population

The aim of this study was to compile the available literature reporting the prevalence of strabismus in Pakistan and calculate the pooled prevalence of strabismus in the Pakistan population. Meta analysis was conducted with 10 studies with a total of...

My top five: Trinkets of fact or fiction

Trinkets of adult wisdom are often delivered to children alongside warnings of catastrophic outcomes. In this article we present five ‘facts’ about eye health and vision and ask the question: to what extent are these ideas backed up by literature?...