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RTP801 as a neuroprotective and axon regenerative treatment
This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...
Risk of developing pseudotumor cerebri in women using a levonorgesteral intrauterine device
Pseudotumor cerebri (PCT) is a disorder causing increased intracranial pressure without a mass lesion, usually seen in obese women of childbearing age. Idiopathic intracranial hypertension is an idiopathic form of the disorder, but several medications have been associated with the...Strengthening the signal: Advancing oculomics research for systemic health insights
Oculomics, the study of how ocular structure reflects systemic health, is poised to become an integral tool for predicting, triaging, and diagnosing a wide range of diseases. By analysing data from the eye, particularly the retina, healthcare providers can gain...Major grant secured to transform immune cell imaging research
A research team has been awarded significant funding by the National Institute for Health and Care Research (NIHR) to develop an innovative drug-device combination that aims to revolutionise how individual immune cells are monitored and treated in patients at Moorfields...The results of the last survey Oct21
This edition’s survey questions moved away from the deep and ethically charged questions of the recent surveys and focussed on simple and straightforward issues. This is really where the surveys began in exploring the minor practice variations which we have...The New Zealand National Eye Centre and the land of the long white cloud
Located southeast of Australia in the South Pacific Ocean, New Zealand (Aotearoa) is home to five million culturally diverse people. Renowned for its lush nature spanning from unexplored forests to active volcanos and snow-capped mountains, New Zealand has become both...Clinical relevance of the anatomic classification of neovascular age-related macular degeneration
The author explains why an OCT-based classification of neovascular AMD is needed and how these neovascular subtypes may help to predict patients’ long-term visual outcome. Age-related macular degeneration (AMD) is a chronic and progressive neurodegenerative process involving the macula in...Feb/Mar 2015 Quiz 1
A 79-year-old male presented to the ophthalmic emergency department with a three week history of left eye pain. He also reported visual deterioration in the left eye over the same period. He suffered from degenerative myopia, with his spectacle prescription...
A case report of Horner syndrome with neuromyelitis optica
This case report details a patient diagnosed with neuromyelitis optica (NMO) with an associated left Horner syndrome. The female patient presented with neck pain and right hemibody decreased pain and temperature sensation. She then went on to develop left ptosis...RNIB and Roche UK launch new eye health audit tool to improve delivery of local eye health services
Leading sight loss charity RNIB (Royal National Institute of Blind People) and Roche UK have today launched a new eye health audit tool: Eye Level.
