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Eye lid lesion

A 46-year-old female farmer was referred by her local GP to the eye department with a history of gradually increasing upper eyelid lesion over 10 weeks, despite the patient being treated with topical and oral antibiotics. The patient was a...

Beyond 2020: An educational video series from the Amazonian rainforest

It has been estimated that one billion people globally live with visual impairment. Moreover, countries in the developing world are disproportionately affected, with four times more low vision than compared to countries with well-established systems of primary, secondary and tertiary...

Macular holes: A brief review

The classification of macular holes has been modernised by OCT findings. This is a brief review and encompasses the historical literature on macular holes. A macular hole is an anatomical discontinuation of the neurosensory retina at the centre of the...

The fragile p-value

Abdus Samad Ansari explores the limitation of the p-value and the application of the fragility index in clinical trials. Clinical trials and tribulations? The restoration of vision or more purely the gift of sight is an aspect of care that...

Good News from Switzerland: A History of Retinal Reattachment Surgery

In one concise volume the reader learns of the recent rapid evolution in vitreoretinal (VR) surgery. The pioneering innovators were often remarkable personalities and this book helps to bring them to life. Prior to 1929 victims of retinal detachment were...

Ophthalmic Aid to Eastern Europe (OAEE)

Peter Cackett, Tim ffytche and Dr Irina Gout reflect on historic ophthalmic aid sent to Eastern Europe. This article was written prior to the horrific events in Ukraine. An appeal for funds and equipment may be made by OAEE later...

The increased use of surgical adjuncts in complex cataract surgeries undertaken in the COVID-19 pandemic

The authors explore whether more complicated cataract operations have been performed in the NHS since the start of the coronavirus pandemic. Restrictions in availability of access to elective cataract surgery during the COVID-19 pandemic and subsequent case prioritisation based on...

Real world data of post-IVT endophthalmitis, from a nurse-delivered intravitreal injection service

Introduction Intravitreal injection of neutralising anti-vascular endothelial growth factor (VEGF) antibody was licenced more than a decade ago, and over the years there has been proportionate increase in the number of intravitreal injections [1]. Injection of a therapeutic agent through...

What effects do repeated Ozurdex implants have in paediatric uveitis?

The aim of this retrospective study was to assess the anatomical and functional results, as well as complications of repeated Ozurdex intravitreal implants in a paediatric (non-infectious) uveitis cohort. Twenty-two eyes (16 patients) received 35 Ozurdex implants over a six...

25-gauge PPV for retained lens fragments

This was a retrospective study including 40 eyes of 40 patients with mean age of 78 years, 19 females and 21 males, who underwent 25-gauge pars plana vitrectomy (PPV) for retained lens fragments with a minimum of six months of...

Comparison of retinal pigment epithelium-choroid graft surgery and anti-VEGF therapy in patients with wet AMD

This was a randomised intervention study in wet AMD patients to investigate benefits of free RPE-choroid graft transplantation surgery versus (continuation of) anti-VEGF treatment. Twenty patients who met the inclusion criteria were subdivided into three subgroups, i.e. RPE tears involving...

Efficacy of intravitreal dexamethasone implant in patients with persistent macular oedema

Chronic cystoid macular oedema (CME) can develop secondary to various pathologies such as diabetic maculopathy, retinal vein occlusion and uveitis. It can cause significant visual impairment and macular damage. The therapeutic effect of corticosteroids in CME is through one or...