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Resveratrol protects against steroid induced intraocular pressure
Topical and systemic steroid delivery is a very effective treatment for many ocular conditions but is compromised by raised intraocular pressure which in turn leads to death of retinal ganglion cells and irreversible blindness. This is an important consideration with...
Sustained elevation of extracellular ATP in chronic glaucoma
Although adenosine 5′-triphosphate (ATP) release from retinal neurons and astrocytes has been demonstrated in short-term increases in intraocular pressure (IOP); such as in aqueous humor of humans with primary acute angle closure glaucoma, the response in chronic IOP elevation was...
Clinical course of vitreomacular adhesion managed by initial observation
The purpose of this study was to investigate the clinical course of patients with idiopathic vitreomacular adhesion (VMA) with a noncomparative case series of patients who had clinical symptoms and spectral-domain optical coherence tomography findings consistent with VMA. The VMA...
Saccadic differences under cover test
Patients with intermittent exotropia and exophoria plus ortho subjects underwent measurement of saccadic reaction times (SRTs) to compare those occurring in one eye and those occurring with alternating cover tests (ACTs). Twenty-five subjects were studied. Results for the intermittent exotropia...
Oral proton pump inhibitors in macular degeneration patients
The authors report five patients with advanced wet macular degeneration and poor vision with onset or enhancement of visual hallucinations with the use of proton pump inhibitors for heartburn management. The hallucinations were reversible with discontinuation of medication. The authors...
Ablepharon-macrostomia syndrome
The ablepharon-macrostomia syndrome is a very rare condition caused by a dominant mutation in the TWIST2 gene. Congenital defects include rudimentary eyelids, macrostomia, ambiguous genitalia and campodactyly. Neonates are at risk of severe corneal exposure without intervention. Previous reports have...
Diffuse lamellar keratitis
This study group reviewed cytokine- and chemokine-mediated mechanisms of diffuse lamellar keratitis (DLK) after lamellar corneal surgical procedures. DLK can occur early or late (months to decades) after all lamellar corneal surgeries, including laser in situ keratomileusis, small incision lenticule...
