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Autophagy in lens mitochondria loss
1 April 2014
| Graham Wallace
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EYE - Cataract, EYE - Refractive
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ATG5, FYCO1, FYVE and coiled coil domain containing 1, LC3B, OFZ, Pik3c3, TOM20, autophagy, autophagy-related 5, cataract, differentiation, electron microscopy, lens, microtubule-associated protein 1 light chain 3B, mitophagy, organelle free zone, phosphatidylinositol 3-kinase, catalytic subunit type 3, translocase of the outer mitochondrial membranes 20 kDa
The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...
Things I’d tell my medical school self, had I known my first year on the job would be during a global pandemic
5 June 2020
| Nikolaos Tzoumas
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EYE - General
In a conversation with his younger self, a foundation doctor reflects on the contrast between his expectations of medicine at university and the reality of working during the coronavirus pandemic. Every doctor arrives at medical school with nervous anticipation, yet...
The role of aspirin in the treatment of NAION: Benefits and controversies
4 December 2024
| Ali Yagan
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EYE - Neuro-ophthalmology
Non-arteritic anterior ischaemic optic neuropathy (NAION) is the most common acute optic neuropathy in individuals over 50 with estimated prevalence of 2–10 per 100,000 people, characterised by sudden, unilateral vision loss due to ischaemic injury to the optic nerve head....
Review of paediatric open globe injuries in the US
This study used the Nationwide Inpatient Sample (NIS) database to describe the trends in types, demographics and incidence of paediatric open globe injuries in the US. The NIS database covers about 97% of the US population and about 20% of...An update on inherited retinal disorders (part 2): Approaches to therapy for IRDs
1 December 2016
| Stacey Strong, Michel Michaelides (Prof)
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EYE - Vitreo-Retinal
Part 1 of this topic can be found here There are currently no proven cures for inherited retinal disease (IRD). However, multiple avenues of research are being investigated to better understand disease mechanisms and trial potential therapies that may slow...
Daybreak Medical: Ophthalmic Ultrasound Seminar 2 Day Course "From Theory to Practice"
30 April 2025
-1 May 2025
Course ProgrammeDay One:-Registration and Welcome-Introduction: applied Basics and Principles-B-Scan: How to Perform and Obtain the Best Images-Standardised A-Scan: Guest Speaker-Biometry: A-Scan, B-Scan and IOL Calculations-Opaque Media/Dense Cataracts-Vitreoretinal Disorders and Trauma-Hands on Training with Real Patients and Biometry Workshop Day Two:-Ultrasound...
Achieving post-op target range increases success of strabismus surgery in adults
This is a retrospective cohort study of all patients over 12-years old undergoing strabismus surgery under a single surgeon in a tertiary referral centre in Toronto, Canada. The aim of the study is to determine the role of achieving immediate...
Mono vs. multi-therapy in IOP control
1 December 2018
| Eulee Seow
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EYE - Glaucoma
This randomised control trial studied newly diagnosed glaucoma patients given mono‐ or multi‐therapy regarding differences in initial intraocular pressure (IOP) reduction, target IOP levels reached and influence of untreated baseline IOP on IOP reduction. Patients newly diagnosed with manifest primary...
EDOF intraocular lens in eyes with preexisting retinal disease
30 May 2025
| Sofia Rokerya
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EYE - Vitreo-Retinal
Extended depth of focus (EDOF) intraocular lens (IOL) offers improved near and intermediate vision, aiming to reduce spectacle dependence in cataract patients. This study aims to evaluate the performance of EDOF lenses following cataract surgery in patients with retinal pathology....
Specialty-driven EMR for paperless clinical environment – insights for an informed choice
1 August 2016
| Rod McNeil
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EYE - General
Deployment of specialty-driven (or specialty-specific) electronic medical record (EMR) systems across UK ophthalmology units appears to be growing rapidly at the expense of generic, multiuse digital technology packages. Experience further suggests that open source systems can play a significant role...
Ophthalmology history and examination – a guide for medical students
15 February 2023
| Abiya Amna Ahmed, Shaan Rashid
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EYE - General
*First author Students have very little exposure to ophthalmology during their years at medical school. Teaching consists of a handful of lectures followed by a short placement in which students are expected to practise histories and examinations on patients with...
CHEC and Royal National Institute for Blind People Launch Strategic Partnership
31 March 2022
CHEC has today announced the launch of a new partnership with the Royal National Institute of Blind People.
